Mechanistic Basis for the Role of Phytochemicals in Inflammation-Associated Chronic Diseases.

Chronic inflammatory diseases occur in a large portion of the population and are associated with a poor diet. Key natural products found in fruits and vegetables may assist in lowering inflammation associated with chronic diseases such as obesity, diabetes, cardiovascular diseases, and cancer. This review seeks to examine the roles of several natural products, resveratrol (RES), quercetin (QUE), curcumin (CUR), piperine (PIP), epigallocatechin gallate (EGCG), and gingerol (GIN), in their ability to attenuate inflammatory markers in specific diseases states.

(4,7,13,16,21,24-Hexaoxa-1,10-diaza-bicyclo-[8.8.8]hexa-cosa-ne)sodium perchlorate.

The title compound, [Na(C(18)H(36)N(2)O(6))]ClO(4), was isolated and crystallized to understand more fully the ligand's binding specificity to cations. The cation and anion reside at an inter-section of crystallographic twofold and threefold axes. The carbon atoms in the cation are disordered over two positions in a 3:2 ratio, and the anion is equally disordered over two positions.

First principles investigation of noncovalent complexation: a [2.2.2]-cryptand ion-binding selectivity study.

A first principles methodology, aimed at understanding the roles of molecular conformation and energetics in host-guest binding interactions, is developed and tested on a system that pushes the practical limits of ab initio methods. The binding behavior between the [2.2.

Low-temperature enantiotropic k2 phase transition in the ionic 222-cryptand complex with LiClO4.

Crystallographic analyses at 100 and 200 K are reported for the macrobicyclic polyether 4,7,13,16,21,24-hexaoxa-1,10-diaza-bicyclo[8.8.8]hexacosane (denoted as 222-cryptand) that encapsulates a Li+ cation and then forms a complex (I) with ClO4-.