Publications by authors named "Joe Hiatt"
PLoS Pathog
December 2023
Article Synopsis
- * gp120 also interacts with the integrin ⍺4β7, which is found on certain memory CD4+ T cells, suggesting that this relationship is important for HIV's preference for these immune cells and gut tissues.
- * The study reveals that CD4 binds to ⍺4β7 dynamically, with specific binding sites that are crucial for both gp120's attachment to CD4 and its entry into cells, indicating that the interaction between CD4 and ⍺4β7 is critical
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