Association of vascular netosis with COVID-19 severity in asymptomatic and symptomatic patients.

We examined from a large exploratory study cohort of COVID-19 patients ( = 549) a validated panel of neutrophil extracellular traps (NETs) markers in different categories of disease severity. Neutrophil elastase (NE), myeloperoxidase (MPO), and circulating nuclear DNA (cir-nDNA) levels in plasma were seen to gradually and significantly ( < 0.0001) increase with the disease severity: mild (3.

The Daalbirrwirr Gamambigu (Safe Children) Model: Embedding Cultural Safety in Child Protection Responses for Australian Aboriginal Children in Hospital Settings.

The aim of this paper is to describe the development of a model of care to embed cultural safety for Aboriginal children into paediatric hospital settings. The Daalbirrwirr Gamambigu (pronounced "Dahl-beer-weer gum-um-be-goo" in the Gumbaynggirr language means 'safe children') model encompasses child protection responses at clinical, managerial and organisational levels of health services. A review of scholarly articles and grey literature followed by qualitative interviews with Aboriginal health professionals formed the evidence base for the model, which then underwent rounds of consultation for cultural suitability and clinical utility.

Low back pain presentations to rural, regional, and metropolitan emergency departments.

Objective: To describe the context of low back pain (LBP) presentations to emergency departments (EDs) by remoteness areas, hospital delineation level and staffing portfolios.

Design: A retrospective observational study using routinely captured ED and admission data over a 5-year period (July 2014-June 2019).

Settings: Thirty seven EDs across a large health district in NSW, Australia, covering major cities, inner regional areas and outer regional areas.

Takutsubo cardiomyopathy and flash pulmonary edema in a trauma patient.

Background: First described in Japanese literature in 1991, Takotsubo cardiomyopathy (TCM), or "broken heart" syndrome, continues to be described in novel circumstances. Commonly mistaken for acute coronary syndrome (ACS) due to similar clinical symptoms and electrocardiogram changes, it usually affects postmenopausal women and those in acute emotional or physical stress. Named for the resemblance of apical ballooning and dyskinesis to the Japanese octopus trap, the pathogenesis is poorly understood.