Editorial: Chronicity of Maltreatment and the Importance of Attachment and Peer Relationships on Youth Mental Health Trajectory.

Childhood maltreatment impacts human development across the life span in most areas of functioning, particularly the onset of mental health symptoms. As our understanding of the biological underpinnings of the effects of maltreatment on childhood development continues to grow, it becomes even more salient to delineate and understand potential variance associated with timing and chronicity of maltreatment. Moreover, as family and peer relationships are known to mediate effects of stress on childhood mental health outcomes, it is important to acknowledge and specifically explore the potential effects of the relational context of a child when stress and trauma are being investigated.

A Developmentally Informed Approach to Address Mass Firearm Violence.

Pediatric medical providers have an important role to play in response to mass gun violence events. Although mass gun violence events are rare, the rate of mass shootings is unfortunately increasing, and such events are shown to have significant and far-reaching psychological impact on children and adolescents. Recommendations from the behavioral health and pediatric fields are consolidated along with developmental considerations to support pediatric provider response in the aftermath of a mass gun violence event.

Understanding Irritability in Relation to Anger, Aggression, and Informant in a Pediatric Clinical Population.

Objective: Despite its clinical relevance to pediatric mental health, the relationship of irritability with anger and aggression remains unclear. We aimed to quantify the relationships between well-validated, commonly used measurements of these constructs and informant effects in a clinically relevant population.

Method: A total of 195 children with primary diagnoses of attention-deficit/hyperactivity disorder, disruptive mood dysregulation disorder, or no major disorder and their parents rate irritability, anger, and aggression on measures of each construct.

The Internal Structure of the Aberrant Behavior Checklist Irritability Subscale: Implications for Studies of Irritability in Treatment-Seeking Youth With Autism Spectrum Disorders.

Given the prominence of the Aberrant Behavior Checklist (ABC), Irritability Subscale (ABC-I), in treatment outcome studies, we conducted a critical examination of its internal consistency and relationship to other measures of irritability in 758 psychiatrically hospitalized youth with autism spectrum disorder. In exploratory and confirmation samples, we conducted factor and bifactor analyses to describe the internal structure of the ABC-I. Our results suggest that the ABC-I roughly represents a unidimensional construct of irritability, as indicated by a general factor in bifactor analysis.

Early life stress: update on neurophysiologic effects and treatment.

Purpose Of Review: Recent research on childhood trauma has focused on the effects of in-utero and early life stress (ELS) as well as improving access to care. This review includes the previous year's clinically relevant research with attention to gaps that require further research that should improve patient care.

Recent Findings: The current article focuses on the latest understanding of ELS effects on the neuroendocrine, inflammatory, immune, and neurologic systems, as well as epigenetic effects with a focus on research examining sex-specific differences.

The many faces of oxytocin: implications for psychiatry.

Oxytocin is known as the 'love hormone' due its role in promoting mother-child and pair bonding. More recent research indicates that oxytocin may have broader pro-social effects on behavior and cognition, which points towards oxytocin's potential as an agent to help improve social cognition and functioning in psychiatric disorders such as schizophrenia and autism. However, new research on oxytocin has also uncovered a 'darker side', including oxytocin's possible role in social out-grouping and envy.