Synopsis of recent research by authors named "Jocylin D Pierro"
- Jocylin D Pierro's recent research centers on the role of all-trans retinoic acid (ATRA) in developmental processes and its implications in predicting toxicity, particularly related to fetal skeletal defects, through innovative methodologies that reduce reliance on animal testing.
- The development of high-throughput screening assays and computational models highlights the significance of ATRA signaling in embryonic morphogenesis and toxicological assessments, promoting alternative approaches for evaluating chemical safety.
- Pierro's work also emphasizes creating comprehensive reference chemical databases to support in vitro testing methodologies, strengthening the predictive value of bioactivity profiles in assessing developmental toxicity related to retinoid pathway disruptions.
