Impact of isoflupredone acetate treatment on clinical signs and weight gain in weanling heifers with experimentally induced Mannheimia haemolytica bronchopneumonia.

Objective: To characterize the impact of Mannheimia haemolytica infection on feed intake and weight gain in feedlot heifers and to evaluate the clinical efficacy of isoflupredone acetate administered in combination with oxytetracycline.

Animals: 96 weanling heifers in a research feedlot facility.

Procedures: Bronchopneumonia was induced by intrabronchial infusion of M haemolytica.