Publications by authors named "Jocelyn Tang"
The incidence of obesity has dramatically increased worldwide. Obesity has been shown to exacerbate the progression of periodontal disease. Studies suggest a sex difference in periodontitis, whereby males are more sensitive to periodontal inflammation compared to females.
View Article and Find Full Text PDFObjectives: This quantitative systematic review evaluated whether pulpotomy performed with hydraulic calcium silicate cements may be used as an alternative to root canal treatment (RCT) in mature permanent teeth with carious pulp exposure.
Data Sources: A comprehensive search was conducted in PubMed, Web of Science, Scopus, and the Cochrane Library. No language restrictions were applied.
NanoDam is a technique for genome-wide profiling of the binding targets of any endogenously tagged chromatin-binding protein , without the need for antibodies, crosslinking, or immunoprecipitation. Here, we explain the procedure for NanoDam experiments in , starting from a genetic cross, to the generation of sequencing libraries and, finally, bioinformatic analysis. This protocol can be readily adapted for use in other model systems after simple modifications.
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- Neural stem cells (NSCs) in the developing nervous system use temporal patterning to differentiate into various neuronal subtypes, with specific transcription factors guiding this process.
- A newly identified transcription factor named Chronophage (or 'time-eater') plays a crucial role in the transition from the Pdm to the Castor temporal windows, similar to mammalian CTIP1 and CTIP2.
- Chronophage not only promotes the shift to generating Castor-associated neurons but also represses earlier neuronal types, showcasing its importance in regulating NSC development and neuron specification.
Article Synopsis
- Temporal patterning in neural progenitors is a key evolutionary strategy for increasing diversity in neurons.
- Researchers developed a method called NanoDam to study how known temporal transcription factors relate to neuronal development in Drosophila.
- The study identified additional factors, Homeobrain and Scarecrow, that are important for defining specific temporal windows in neural development and have similar roles in the visual systems of other species.
Background: The evolutionary origin of the telencephalon, the most anterior part of the vertebrate brain, remains obscure. Since no obvious counterpart to the telencephalon has yet been identified in invertebrate chordates, it is difficult to trace telencephalic origins. One way to identify homologous brain parts between distantly related animal groups is to focus on the combinatorial expression of conserved regionalisation genes that specify brain regions.
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- The study of heart size and shape regulation in Astyanax mexicanus reveals distinct morphological differences between river-dwelling (epigean) and cave-dwelling (troglomorph) fish, with troglomorphs having smaller, rounder hearts.
- Heart size differences emerge as early as 24 hours post-fertilization, while shape variations become evident at 2 days post-fertilization, suggesting genetic factors at play.
- Notably, functional differences are also seen, as troglomorphs exhibit slower heart rates, providing a potential basis for understanding cardiac development and related human health issues.
Lifespan and health in older age are strongly influenced by diet. Feeding diets high in sugar has increasingly been used as an experimental model to understand the physiological effects of unhealthy, contemporary human diets. Several metabolic parameters and physiological responses to nutrition are known to be dependent on the sex of the animal.
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