Publications by authors named "Jocelyn S Bel"
Article Synopsis
- Adipose tissue comes in two main types: white (WAT) for fat storage and brown (BAT) for heat production; active BAT is linked to better metabolism.* -
- Chronic stress hormone exposure (corticosterone) was studied in mice to see how it affects BAT, revealing it can take on a white-like phenotype with increased body weight and insulin resistance.* -
- The study found that this "whitening" of BAT under stress involves higher expression of uncoupling protein 1 (UCP-1), suggesting a potential metabolic dysfunction that affects glucose metabolism.*
Accumulation of white adipose tissue (WAT) underlies the obesity epidemic, leading to current therapeutic techniques that are being investigated for their ability to activate/"beige" this tissue. Adipose tissue (AT) beiging has been reported through intermittent cold exposure (CE), exercise, and β3-Adrenergic Receptor (β3AR) agonists. But how AT beiging can help in the treatment of metabolic disorders like obesity and type 2 diabetes (T2D) remains largely unexplored.
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