Implant of mesenchymal cells decreases acute cellular rejection in small bowel transplantation.

Objective: The objective of the study was to show adipose tissue-derived mesenchymal stem cells (AD-MSCs) immunomodulatory effects in small bowel transplantation (SBTx).

Materials And Methods: Forty Wistar Han rats (age: 10-12 weeks): were allogenic receptor rats and were allotted in 2 groups. Control group: rats undergoing orthopic SBTx ; AD-MSCs group: rats undergoing orthotopic SBTx plus AD-MSCs.

Evaluation of Institut Georges Lopez-1 preservation solution in pig pancreas transplantation: a pilot study.

Background: Institut Georges Lopez-1 preservation solution (IGL-1) is an emerging extracellular-type electrolyte solution, low in viscosity, containing polyethylene glycol 35 as a colloid. Although IGL-1 has shown beneficial outcomes in kidney and liver preservation, this pilot study is the first to evaluate the efficacy of IGL-1 in pancreas transplantation (PT) compared with the University of Wisconsin solution (UW).

Methods: Sixteen Landrace pigs underwent allogeneic PT with 16 hr of cold ischemia.

Fragment C tetanus toxin: a putative activity-dependent neuroanatomical tracer.

The non-toxic C fragment of tetanus toxin fused to the beta-galactosidase enzyme was analysed as a neuroanatomical tracer. After intramuscular injection in rat tongue, its location in the hypoglossal network was compared with other classic tracers such as neurotropic viruses. The hybrid protein reached second and higher-order neurons after crossing several synapses.