Objective: Our objective was to validate a previously published simple ultrasound (US) score for Crohn's disease (CD).
Methods: A total of 107 CD patients from 2 hospitals prospectively underwent both ileocolonoscopy (reference standard) and US as part of their clinical care. Endoscopic activity was assessed using the Simple Endoscopic Score for Crohn's Disease (SES-CD) and was also categorized as absent, mild (inflammation without ulcers), or severe (presence of ulceration).
Objective: Our goal in this multicentric prospective study was 2-fold: first, to test the diagnostic accuracy of ultrasound, color Doppler imaging (CDI), and contrast-enhanced ultrasound (CEUS) in identifying disease activity in patients with Crohn's disease (CD) compared with endoscopy as the reference standard; and, second, to construct a sonographic score that allows disease activity to be detected.
Materials And Methods: Seventy-two patients with CD from 3 hospitals underwent within a 30-day period both colonoscopy and ultrasound (US), including mural thickness, CDI, and CEUS, prospectively as part of clinical care. A multivariate analysis was carried out to assess the influence of each of the ultrasound variables in predicting endoscopic activity.
Background: Current guidelines do not address the post-sustained virological response management of patients with baseline hepatitis C virus (HCV) cirrhosis and oesophageal varices taking betablockers as primary or secondary prophylaxis of variceal bleeding. We hypothesized that in some of these patients portal hypertension drops below the bleeding threshold after sustained virological response, making definitive discontinuation of the betablockers a safe option.
Aim: To assess the evolution of portal hypertension, associated factors, non-invasive assessment, and risk of stopping betablockers in this population.