Chondrogenic differentiation of mesenchymal stem/stromal cells on 3D porous poly (ε-caprolactone) scaffolds: Effects of material alkaline treatment and chondroitin sulfate supplementation.

Cartilage defects resultant from trauma or degenerative diseases (e.g., osteoarthritis) can potentially be repaired using tissue engineering (TE) strategies combining progenitor cells, biomaterial scaffolds and bio-physical/chemical cues.

Solvent tolerance in bacteria: role of efflux pumps and cross-resistance with antibiotics.

Microorganisms have mechanisms that enable them to tolerate lethal concentrations of toxic compounds. This feature has been exploited in a wide range of bioprocesses that range from bioremediation applications to production of fine chemicals in two-phase reaction media. The ability to modify the physical properties of cellular membranes has long been put forward as a protection mechanism that enables microorganisms to tolerate solvents.