Publications by authors named "Joao Vitor Pereira Leite"
Article Synopsis
- * The research analyzed samples from three canine OMM cell lines and human melanoma cell lines, identifying a total of 500 mutated genes in dogs, including notable ones like EP300 and NOTCH1, with 82 mutations shared between dogs and humans.
- * These findings offer important insights for understanding the genetic landscape of OMMs and could lead to the development of new treatment options for both canine and human patients in the future.
Methylene blue and photodynamic therapy for melanomas: Inducing different rates of cell death (necrosis and apoptosis) in B16-F10 melanoma cells according to methylene blue concentration and energy dose.
Murilo Penteado Del Grande Andréa Midory Miyake Márcia Kazumi Nagamine João Vitor Pereira Leite Ivone Izabel Mackowiak da Fonseca
Photodiagnosis Photodyn Ther
March 2022
Background: Photodynamic therapy (PDT) is a cancer treatment based on the interaction between the photosensitizing agent methylene blue (MB), light, and molecular oxygen. MB has antibacterial properties and can to bind to melanin. Here, we investigated whether MB based PDT (MB-PDT) could decrease viability and induce death of murine melanoma B16-F10 cells.
View Article and Find Full Text PDFLineu (Euphorbiaceae) is a tropical and subtropical ornamental and toxic plant. produces a latex that is commonly used to treat neoplasms. This study aimed to evaluate the effects of diluted latex (DETL) on human (SK-MEL-28) and canine (CBMY) melanoma cells.
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