Publications by authors named "Joao V Perez de Souza"

Background: Perinatal mortality remains a global challenge. This challenge may be worsened by the negative effects of the COVID-19 pandemic on maternal and child health.

Objectives: Examine the impact of the COVID-19 pandemic on perinatal care and outcomes in the Tamale Teaching Hospital in northern Ghana.

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The scope of the study was to analyze original preclinical studies on the antimicrobial effects of carvacrol and derivatives on the genus. According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, four databases (PubMed, Web of Science, SCOPUS and EMBASE) were searched. The search retrieved 392 records, of which 11 papers were selected.

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To review , , and studies examining the antibacterial and immunomodulatory properties of piperine (PPN). This systematic review followed PRISMA guidelines, and five databases were searched. A total of 40 articles were included in this study.

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Current treatments for leishmaniases are not satisfactory, thus alternatives are needed. We searched for clinical trials with immunotherapeutic approaches for patients with leishmaniasis. Out of 205 articles, 24 clinical trials were selected, and eight submitted to meta-analysis.

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The activity of rifampin (RIF) and piperine was evaluated at the relative transcript levels of 12 efflux pumps (EPs), and an additional mechanism was proposed to be behind the synergic interactions of piperine plus RIF in AutoDock v4.2.3 and Molegro v6 programs were used to evaluate PIP binding in RNA polymerase (RNAP).

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