Cocaine abuse and effects in the serum levels of cytokines IL-6 and IL-10.

Background: Cocaine abuse is capable of activating the innate immune system in the CNS resulting in deregulation of homeostasis between pro and antiinflammatory cytokines. The aim of this study was to investigate serum levels of pro and antiinflammatory cytokines, IL-6 and IL-10 respectively, in cocaine users from a young population-based sample.

Methods: This is a case-control study nested in a cross-sectional population-based survey, with individuals of 18 and 35 years old.

Stress, depression, quality of life and salivary cortisol levels in community health agents.

Objective: To determine the prevalence of and factors associated with depression and stress with perceived quality of life and the salivary cortisol levels in Community Health Agent (CHA). Materials and Methods Cross-sectional descriptive study of CHAs in Pelotas-RS, Brazil. Data collection, including sociodemographic information and factors related to work and health.