Publications by authors named "Joao Paulo Caldas"

Malaria is frequently associated with splenomegaly. However, spontaneous splenic rupture is a rare and life-threatening complication. It is mostly seen in acute infection in non-immune adults and Plasmodium vivax and Plasmodium falciparum have been associated with the majority of cases.

View Article and Find Full Text PDF

Background: COVID-19 is mainly characterized by respiratory manifestations. Nevertheless, neurologic complications have been described, including delirium, which appears to be frequent, prolonged, and severe.

Methods: We conducted a retrospective analysis of demographic, clinical, and laboratory data of two cohorts: patients with COVID-19 admitted to the infectious disease intensive care unit (ID-ICU) and patients admitted to the ID-ICU with other respiratory infections in 2018-2019.

View Article and Find Full Text PDF

Septic shock is the most dreaded presentation of an infection, carrying a reserved prognosis. Appropriate antimicrobial therapy is therefore the mainstay of treatment, alongside organ support as needed. Legionnaires' disease is mainly due to serogroup 1 but it can be caused by other serogroups and species not detected by the urinary antigen test.

View Article and Find Full Text PDF
Article Synopsis
  • Influenza virus causes serious respiratory infections, leading to significant healthcare burdens, with a study examining predictors of severity and mortality in hospitalized patients.
  • Researchers conducted a retrospective analysis of 221 hospitalized influenza cases over two years, finding that 16.7% of patients died and 45.7% experienced severe illness.
  • C-reactive protein (CRP) was identified as the only independent predictor of both severity and in-hospital mortality, showing increased risks of complications and death with higher CRP levels.
View Article and Find Full Text PDF

The failure of artemisinin combination therapy (ACT) in malaria patients returning from endemic regions may be driven by parasite resistance to this treatment. ACT is used globally as the first-line treatment for Plasmodium falciparum malaria. However, artemisinin-resistant strains of P.

View Article and Find Full Text PDF

Botulism is an acute toxin-mediated neuroparalytic syndrome caused by some species. It typically presents itself as an acute symmetric descending paralysis of cranial and peripheral nerves, which can potentially evolve to respiratory failure and death. We report a case of botulism diagnosed in a patient presenting with a parotitis probably due to xerostomia, even though he had already sought medical assistance for blurred vision and dysphagia.

View Article and Find Full Text PDF

is a basidiomycetes worldwide distributed that has emerged as cause of invasive infections in immunosuppressed patients. We present a case of a man who was simultaneously diagnosed with a small cell non-Hodgkin lymphoma and a sphenoid sinusitis by . Intraoperative observation and histology description were crucial to consider an alternative diagnosis to mucormycosis suggested by the MRI.

View Article and Find Full Text PDF