Rise and fall of Caspofungin: the current status of Caspofungin as a treatment for infection.

Antifungal infections are becoming a major concern to human health due to antimicrobial resistance. Echinocandins have been promising agents against resistant fungal infections, primarily caspofungin, which has a more effective mechanism of action than azoles and polyenes. However, fungi such as appear to be inheritably resistant to these drugs, which is concerning due to the high clinical importance of .