Myricetin, the Main Flavonoid in Leaf, Is a Novel Inhibitor of Platelet Thiol Isomerases PDI and ERp5.

Background: Flavonoids have been characterized as a prominent class of compounds to treat thrombotic diseases through the inhibition of thiol isomerases. is a flavonoid-rich medicinal plant that contains myricetin and gallic acid. Little is known about the potential antiplatelet properties of and its constituent flavonoids.

Reproductive alterations in hyperinsulinemic but normoandrogenic MSG obese female rats.

Obesity and metabolic syndrome are the common causes of reproductive and fertility disorders in women. In particular, polycystic ovary syndrome, which is clinically characterized by hyperandrogenism, oligo/anovulation, and polycystic ovarian morphology, has been increasingly associated with metabolic disorders. However, given the broad interplay between metabolic and reproductive functions, this remains a field of intense research.