Publications by authors named "Joao H Marques"
Purpose: To study corneal epithelial thickness in patients with Dry Eye Disease (DED), according to symptomatology.
Patients And Methods: Cross-sectional study in the outpatient clinic of the Ophthalmology Department of a tertiary hospital in Oporto, Portugal. Adult patients with a clinical diagnosis of dry eye disease were eligible for participation.
Purpose: To describe a series of patients with hereditary transthyretin amyloidosis (ATTRv) with vitreous amyloid and to study the efficacy and safety of pars plana vitrectomy (PPV) for its treatment.
Methods: Retrospective study of 266 patients with ATTRv due to Val30Met mutation submitted to PPV for vitreous amyloid, with a minimum 3-month follow-up. Indications for surgery were disabling myodesopsia or 2 lines loss in visual acuity.
Intraocular lens power calculation: angle κ and ocular biomechanics.
J Cataract Refract Surg
April 2024
Purpose: To study the effect of ocular biomechanics on the prediction error of intraocular lens (IOL) power calculation.
Setting: Centro Hospitalar Universitário do Porto, Porto, Portugal.
Design: Prospective longitudinal study.
Purpose: To evaluate the agreement between conventional fundus photography (CFP) and multicolor fundus imaging (MFI) for the detection of lesions of diabetic retinopathy (DR) and retinal vein occlusion (RVO).
Methods: Cross-sectional analysis of eyes with DR or RVO who underwent CFP and MFI. All images were independently analyzed by two observers (O1 and O2), and the evaluated lesions were classified as "present" or "absent".
Purpose: To compare different light-based devices, namely, intense pulsed light (IPL) and IPL with low-level light therapy (LLLT), in the treatment of meibomian gland dysfunction (MGD).
Methods: This was a prospective, observational study that included patients with MGD. Group 1 included 58 eyes treated with IPL (eye-light®, Espansione Marketing S.
Prcis: In this study, patients with glaucoma undergoing topical antihypertensive (TAH) drugs had changes in the ocular surface and more dry eye symptoms than controls. Clinicians should recognize the influence of TAH drops on exacerbating ocular surface disease.
Purpose: The purpose of this study was to evaluate the ocular surface of eyes with glaucoma treated with TAH drugs.
Purpose: To report a case of acute macular neuroretinopathy (AMN) following SARS-CoV-2 vaccination.
Methods: Case report.
Results: An otherwise healthy 28-year-old white woman presented to an ophthalmology department with complaints of black paracentral vision scotomata on both eyes that appeared 2 days after receiving the first dose of Vaxzevria vaccine.
Purpose: To study the clinical benefit of low-level light therapy when associated with intense pulsed light for the treatment of meibomian gland dysfunction.
Methods: An observational study. Two groups of patients that were treated with IPL were considered: group 1 (31 subjects, 62 eyes), intense pulsed light followed by low-level light therapy and group 2 (31 subjects, 62 eyes) intense pulsed light alone.
Purpose: To review the indications and efficacy of Intense Pulsed Light (IPL) application in the treatment of Meibomian Gland Dysfunction (MGD). Its main purpose is to describe its physiology, efficacy, indications, and adverse effects.
Patients And Methods: A two database (PubMed, EMBASE) search was performed from July 2017 to July 2022 using the MeSH terms ("Intense Pulsed Light" AND ("Meibomian Gland Dysfunction" OR "Dry Eye").
Background: There have been increased reports of dry eyes in the coronavirus disease 2019 (COVID-19) pandemic era.
Aim: To analyze the differences in tear film properties from pre- and post-pandemic of the COVID-19 era.
Methods: It was a retrospective comparative study.
Article Synopsis
- Retinal angiopathy linked to hereditary transthyretin amyloidosis (ATTRv) can lead to permanent vision loss if not treated; researchers aimed to review the clinical and imaging features related to this condition and develop a monitoring strategy for affected patients.
- Common clinical symptoms include abnormal retinal blood vessels, hemorrhages, and amyloid deposits, while imaging techniques reveal significant issues such as delayed blood flow and ischemia.
- It is crucial for ATTRv patients to have regular check-ups to manage retinal angiopathy effectively, and treatment options like photocoagulation and anti-growth factor injections are available; ATTRv should be considered when diagnosing unexplained retinal issues.
Phakic intraocular lens explantation: series of 175 surgeries.
J Cataract Refract Surg
September 2022
Purpose: To evaluate the indications for pIOL explantation, pIOL survival time, and visual outcomes and access endothelial cell loss (ECL) after explantation.
Setting: Ophthalmology Department, Centro Hospitalar Universitário do Porto, Portugal.
Design: Retrospective longitudinal study.
Choroidal changes and associations with visual acuity in diabetic patients.
Int J Retina Vitreous
January 2022
Background: The variable visual function observed in diabetic retinopathy (DR) patients is not fully explained by the classic staging system. Our purpose was to evaluate choroidal changes, in standardized sectors, in DR patients and to find associations between choroidal measurements and visual function.
Methods: Cross-sectional study that included the right eye of diabetic patients (n = 265) without active edema, ischemia or neovascularization and age-matched controls (n = 73).
Purpose: To analyze the visual performance in contact lens wearers with keratoconus.
Methods: A retrospective study including contact lens (CL) wearers was performed. The current best-corrected visual acuity with contact lens (BCVA-CL) and with spectacles (BCVA-S) correction, contrast sensitivity (CS) (by Metrovision-MonPack3), analysis of light scattering in the retina and vision break-up time (HD Analyzer), and corneal tomography (Oculus Pentacam HR) were evaluated.
Purpose: To compare the choroidal characteristics between the eyes of patients with and without hereditary transthyretin amyloidosis.
Methods: Case-control observational study with choroidal thickness and vasculature evaluation by optical coherence tomography with enhanced depth imaging protocol of the macula.
Results: The study included 332 eyes: 166 eyes of hereditary transthyretin amyloidosis patients and 166 eyes of healthy patients.
Aim: Diabetic retinopathy staging system and progression predictors are soon to be considered insufficient for ophthalmologic practice. Given the growing evidence of the role of choroidal dysfunction, our purpose was to assess choroidal vascular changes with intravitreal ranibizumab (RBZ) treatment in diabetic macular edema (DME).
Methods: This was a prospective longitudinal cohort study.
Background: Cystoid macular edema (CME) due to Irvine-Gass syndrome (IGS) is one of the common causes of painless visual impairment post-cataract extraction. The treatment of recurrent cases remains unstandardized.
Objective: To evaluate the effectiveness and safety of fluocinolone acetonide intravitreal implant (0.
Purpose: To describe the tomographic and corneal biomechanical status of a sample of eyes excluded from LVC and to present the differences in biomechanical behavior in relation to cutoffs of clinical- and tomography-based screening methods used in clinical practice.
Patients And Methods: Observational cross-sectional study including 61 eyes from 32 consecutive patients who were excluded from LVC in our department. Clinical and demographic data were collected from the patients' clinical records.
Objective: To automatically study the pupillary light reflex in patients with hereditary transthyretin-associated amyloidosis (hATTR).
Methods: Prospective cross-sectional observational study in patients with hATTR with unilateral scalloped iris. Pupillary light reflex of scalloped iris eyes (21 eyes) were compared with non-scalloped iris eyes (21 eyes, paired eyes of the same patients) and also with a control group of 20 healthy eyes, using static and dynamic pupillometry with the Metrovision MonPack One.
Purpose: To assess the outcomes of vitrectomy with or without cataract surgery for the treatment of idiopathic ERM in phakic eyes and evaluate predictors of functional and anatomical outcomes.
Methods: Retrospective cohort of consecutive phakic ERM eyes distributed in three groups: a) combined (phacovitrectomy) group, b) PPV-only group, and c) consecutive group (PPV followed by cataract surgery). Main outcomes were final visual acuity (VA) and cystoid macular edema (CME) occurrence.
Purpose: To describe the anatomical and functional results of the implantation of asymmetric thickness intracorneal ring segments (AS-ICRS) in eyes with keratoconus and asymmetric/irregular astigmatism (type 2 - and type 3 - phenotypes, Fernandez-Vega/Alfonso morphologic Keratoconus classification).
Materials And Methods: Retrospective observational study including 19 consecutive patients (21 eyes) with keratoconus who underwent manual implantation of the Keraring Asymmetric ICRS (AS). Analysis included demographic and clinical data and Pentacam (Oculus) measurements: topographic astigmatism; topographic flat meridian (K1), steepest meridian (K2) and the maximum keratometric point (Kmax); total root mean square (RMS) and high order RMS (HOA) aberrations and comatic Zernike coefficients (Z3;Z3) at 0º and 90º meridians.