Research misconduct in health and life sciences research: A systematic review of retracted literature from Brazilian institutions.

Background: Measures to ensure research integrity have been widely discussed due to the social, economic and scientific impact of research integrity. In the past few years, financial support for health research in emerging countries has steadily increased, resulting in a growing number of scientific publications. These achievements, however, have been accompanied by a rise in retracted publications followed by concerns about the quality and reliability of such publications.

Pseudonormalization of transmitral pulsed doppler flow: A/e' ratio during the valsalva maneuver--a new discriminative index.

Unlabelled: The Valsalva maneuver (VM) has frequently been suggested as a useful method in evaluation of left ventricular (LV) grade II diastolic dysfunction (DDII) through inversion of a pseudonormalized ratio between diastolic transmitral early (E) and late atrial (A) waves assessed by pulsed Doppler. The purpose of our study was to determine the sensitivity and specificity of E/A inversion during VM in LV DDII patients and its correlation with mitral annulus motion evaluated by tissue Doppler imaging (TDI). Using the echocardiographic criteria of the European Society of Cardiology for the diagnosis of diastolic dysfunction, we studied a group of 44 patients, 27 male, aged 59 +/- 14 years, with DDII (DDII-group) and compared them with a control group (N group) composed of 33 healthy individuals, 17 male, aged 36 +/- 9 years.

Contrast echocardiography in segmental analysis and intraventricular gradient quantification in hypertrophic cardiomyopathy.

Introduction: Hypertrophic cardiomyopathy (HCM) is a hereditary disorder characterized by ventricular hypertrophy, diastolic dysfunction and hyperdynamic left ventricular systolic function. This excessive contraction is sometimes associated with significant intraventricular pressure gradients. These gradients are dynamic and therefore vary at different times.