What is the effect of Tribulus terrestris on testicular morphology and sperm production? An experimental study in the rat model.

The objective of this study was to investigate whether treatment with Tribulus terrestris (Tt) has any impact on the testicular morphology and function in a rodent model. Twenty male rats were divided into a control group and a group receiving 100 mg kg -1 body weight of Tt supplementation. After 40 days of experiment, the animals were submitted to euthanasia; epididymal tail spermatozoa were collected; and spermatozoa concentration, motility, and viability were analyzed.

Pediatric Organ and Tissue Donation-A 10-Year Retrospective Study in Portugal.

Organ and tissue donation can transform lives. One donor can ensure the survival of up to 8 people through their organs and improve the quality of life for dozens more through tissue donation. Portugal has an excellent transplantation rate, but deaths still occur while waiting for an organ.

Does treatment with dutasteride or finasteride has impact on renal morphology? Experimental study.

Purpose: To investigate whether renal modifications occur following treatment with dutasteride or finasteride.

Methods: Twenty-four male rats were divided into three groups: control (that received distilled water), dutasteride (0.5 mg/kg/day), and finasteride (5 mg/kg/day) groups.

Factors associated with health-related quality of life changes in survivors to pediatric intensive care.

Objective: To determine predictors of change in the health-related quality of life in survivors to pediatric intensive care, based on preadmission health status, demographic characteristics, and physiological variables.

Design: Prospective evaluation of health-related quality of life at PICU admission and after 6 months.

Setting: Three PICUs at tertiary hospitals.

[Cardiac arrest in the pediatric population].

A case of cardiac arrest in a ten year old child that was successfully resuscitated is here presented. The etiological investigation showed an Hypertrophic Cardiomyopathy (HCM). An Implantable Cardioverter Defibrillator (ICD) was placed for secondary profilaxy of Sudden Death (SD).

[Lúpus erythematosus].

Systemic Lúpus Erythematosus (SLE) is an auto-imune disorder, with multiple organ involvement, characterized by vascular and connective tissue inflammation, as well as antinuclear antibodies (ANA). We report a case of a black teenager with a past of arthritis of knees, fever and astenia during the year previous to this admission. She was admitted to the Pediatric Intensive Care Unit (PICU) for bilateral Streptococcus pneumoniae pneumonia complicated by pleural effusion.

Methadone intoxication in a child: toxic encephalopathy?

Methadone is used in the treatment of opioid addiction. Acute intoxication can lead to severe consequences and can even be lethal. In several case reports and small series, a presumably toxic leukoencephalopathy is described resulting from inhalation of heroin.