Crit Rev Oncol Hematol
January 2025
Background: Patients with Down syndrome (DS) have a unique genetic and clinical profile that may increase the risk of cancer.
Methods: A literature search on PubMed, Scopus, Web of Science, and the Cochrane databases was conducted, focusing on studies to investigate the prevalence of solid and hematologic tumors in DS.
Results: Fifteen studies were included, encompassing 62,121 individuals with Down syndrome (DS).