First hospital outbreak of the globally emerging in a European hospital.

Background: is a globally emerging multidrug resistant fungal pathogen causing nosocomial transmission. We report an ongoing outbreak of in a London cardio-thoracic center between April 2015 and July 2016. This is the first report of in Europe and the largest outbreak so far.

Antifungal effect of mouth rinses on oral Candida counts and salivary flow in treatment-naïve HIV-infected patients.

Oral candidiasis is a major problem in developing countries where antiretroviral therapy is available to a small percentage of the infected population. HIV patients are prone to xerostomia and predisposed to Candida infection. Preventing oral candidiasis is better than the frequent use of antifungals that may lead to the development of drug resistance.

Effect of antifungal treatment on the prevalence of yeasts in HIV-infected subjects.

Oral candidiasis, the most common opportunistic infection in patients with HIV infection, is usually associated with Candida albicans. Several factors may influence the carriage of Candida, including immunocompromised conditions and HIV infection, colonization by yeasts from different geographical areas and antimycotic treatment. This study investigated the Candida carrier rate, level and types of yeast in HIV-positive and -negative subjects, and the effect of previous exposure to antifungal drugs on the level of yeasts in HIV-positive patients in Gauteng, South Africa.