Background Identifying early signs of a SARS-CoV-2 infection in healthcare workers could be a critical tool in reducing disease transmission. To provide this information, both daily symptom surveys and wearable device monitoring could have utility, assuming there is a sufficiently high level of participant adherence. Purpose The aim of this study is to evaluate adherence to a daily symptom survey and a wearable device (Oura Ring) among healthcare professionals (attending physicians and other clinical staff) and trainees (residents and medical students) in a hospital setting during the early stages of the COVID-19 pandemic.
View Article and Find Full Text PDFPurpose: Meta-analyses of observational studies reduce the role of chance but also introduce bias because the individual component studies are not randomized. Further, it is plausible that the bias may be different in case-control and cohort studies. We explored these issues in meta-analyses of observational studies of Opioid Use Disorder (OUD).
View Article and Find Full Text PDFBreast Cancer Res Treat
November 2014
Research on the effect of cardiorespiratory (CR) exercise on upper extremity (UE) limb volume is limited in women with breast cancer-related lymphedema (BCRL). The aim of this study was to compare changes in UE volume immediately following a symptom-limited CR treadmill test in women with and without BCRL. As part of a cross-sectional study, 133 women post unilateral BC treatment completed symptom-limited treadmill testing.
View Article and Find Full Text PDFFollowing breast cancer (BC) treatment, many women develop impairments that may impact cardiorespiratory (CR) fitness. The aims of this study were to 1) evaluate CR fitness in women following BC treatment, 2) evaluate differences in CR fitness in those with and without breast cancer-related lymphedema (BCRL) and compare these to age-matched norms, and 3) evaluate the contribution of predictor variables to CR fitness. 136 women post-BC treatment completed testing: 67 with BCRL, and 69 without.
View Article and Find Full Text PDFPatients with end-stage renal disease (ESRD) requiring renal replacement have impaired health-related quality of life (HRQoL), and there is general consensus that HRQoL improves with successful transplant and evidence of improvement with frequent hemodialysis. This study reports changes in HRQoL associated with changes in treatment modality to daily hemodialysis (DHD) and transplant among patients requiring renal replacement. This cohort study had assessments at baseline and 6-month following modality change.
View Article and Find Full Text PDFBackground: Exercise capacity as measured by peak oxygen uptake (Vo₂(peak)) is low in hemodialysis patients. The present study assesses determinants of VO₂(peak) in patients with chronic kidney failure who either changed kidney replacement modality to frequent hemodialysis therapy or received a kidney transplant.
Study Design: Cohort study with assessment at baseline and 6 months after modality change.
Objectives: To determine whether objectively measured physical activity levels are associated with physical function and mobility in older men.
Design: Cross-sectional.
Setting: Academic research center.
Background: Testosterone supplementation has been shown to increase muscle mass and strength in healthy older men. The safety and efficacy of testosterone treatment in older men who have limitations in mobility have not been studied.
Methods: Community-dwelling men, 65 years of age or older, with limitations in mobility and a total serum testosterone level of 100 to 350 ng per deciliter (3.
Background: Few studies have evaluated an individualized home-based exercise prescription during and after cancer treatment.
Objective: The purpose of this study was to evaluate the effectiveness of a home-based exercise training intervention, the Pro-self Fatigue Control Program on the management of cancer-related fatigue.
Interventions/methods: Participants (N = 119) were randomized into 1 of 3 groups: group 1 received the exercise prescription throughout the study; group 2 received their exercise prescription after completing cancer treatment; and group 3 received usual care.
Context: Mobility limitation is associated with increased morbidity and mortality. The relationship between circulating testosterone and mobility limitation and physical performance is incompletely understood.
Objective: Our objective was to examine cross-sectional and prospective relations between baseline sex hormones and mobility limitations and physical performance in community-dwelling older men.
Background: Interest in the quantification of physical activity is on the rise. Triaxial accelerometry has frequently been used; however, research on the reliability of these devices is limited. We examine the interunit and intraunit reliability of 22 RT3 triaxial accelerometers using a performance-documented laboratory agitator.
View Article and Find Full Text PDFUnlabelled: Nonalcoholic fatty liver disease (NAFLD) has been referred to as the hepatic manifestation of the metabolic syndrome. There is a lower prevalence of metabolic syndrome in individuals with higher health-related fitness (HRF) and physical activity (PA) participation. The relationship between NAFLD severity and HRF or PA is unknown.
View Article and Find Full Text PDFStudies of exercise capacity in children with chronic kidney disease (CKD) are limited. We tested 25 pediatric kidney transplant (TX) recipients and 15 pediatric dialysis (DX) patients. Nine children in the DX group received kidney transplants and were retested 3 months following surgery (pre/post).
View Article and Find Full Text PDFBackground: Pediatric organ transplant recipients may have elevated cardiovascular (CV) risk. Low cardiorespiratory fitness (CRF) may contribute to CV risk; however, studies of CRF in children following kidney transplantation (KTx) and liver transplantation (LTx) are limited.
Methods: Laboratory testing included assessment of CRF (VO2peak), muscle strength, and body composition (%fat).
Many studies have reported improved health-related quality of life (HRQoL) from pre- to immediate post-orthotopic liver transplantation (OLT). However, few studies have evaluated longitudinal changes over the first 2 yr post-OLT and none have simultaneously examined objective measures of health-related fitness. A total of 50 OLT recipients (32 males,18 females; 51.
View Article and Find Full Text PDFExercise capacity and muscle function are known to be abnormal in patients with renal disease. We present a case study in which we studied a kidney transplant recipient who received a kidney from his identical twin. Testing included maximal exercise testing with measurement of oxygen uptake (VO2max), isokinetic muscle function testing, body composition analysis using dual energy X-ray absorptiometry (DEXA) imaging and quality of life using The Medical Outcomes Short Form (SF-36) questionnaire.
View Article and Find Full Text PDFEnd-stage liver disease (ESLD) affects thousands of people in the United States annually. Improvements in survival after liver transplantation have broadened the indications for its use as a proven therapy for ESLD, rapidly increasing the number of transplant candidates. However, the number of patients awaiting transplantation far surpasses the donor supply, resulting in lengthy waiting times.
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