Publications by authors named "Joanna Zuk-Kuwik"
Article Synopsis
- The study examines lupus nephritis (LN) in patients with systemic lupus erythematosus (SLE), comparing characteristics of those diagnosed early (within one year of SLE) versus those diagnosed later (more than one year after SLE).
- It analyzed medical records from 331 LN patients treated at a Polish hospital between 2012 and 2022, focusing on demographics, clinical details, and laboratory test results, with statistical methods used to identify key factors affecting LN development.
- Findings indicate that delayed-onset LN patients are generally younger at SLE diagnosis and exhibit more severe symptoms, along with a higher occurrence of specific autoantibodies, highlighting the importance of monitoring and early diagnosis in non-LN SLE
Asthma heterogeneity complicates the search for targeted treatment against airway inflammation and remodeling. We sought to investigate relations between eosinophilic inflammation, a phenotypic feature frequent in severe asthma, bronchial epithelial transcriptome, and functional and structural measures of airway remodeling. We compared epithelial gene expression, spirometry, airway cross-sectional geometry (computed tomography), reticular basement membrane thickness (histology), and blood and bronchoalveolar lavage (BAL) cytokines of = 40 moderate to severe eosinophilic (EA) and non-eosinophilic asthma (NEA) patients distinguished by BAL eosinophilia.
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