[Soft tissue sarcomas of the parameningeal region in children--own observations].

Unlabelled: Soft tissue sarcomas (STS) non-Hodgkin's lymphomas and less frequently nasopharyngeal carcinomas are the most common malignancies located in the parameningeal region in children.

Aim: To assess diagnostic and therapeutic problems in children with parameningeal STS treated in the Departments of Paediatric Oncology in Gdansk and Lublin between 1992 and 2006.

Material And Methods: The study includes 17 patients with parameningeal STS; mean age of patients was 5.

[Clinical characteristics and therapy outcome in children with stage IV Hodgkin's lymphoma--the experience of two oncological centres].

Unlabelled: The cure rate in children with Hodgkin's disease (HD), at present time exceeds 90% but the prognosis in stage IV HD is much worse. THE AIM of the study was to analyze the initial symptoms, course and results of oncological therapy in children with stage IV of Hodgkin's disease.

Material And Methods: The analyzed group comprised of 15 patients with IV stage HD (M/F: 11/4, mean age: 12 years), treated from January 1993 to March 2005, in two Polish centres of paediatric oncology in Gdansk and Lublin.

[Solid neoplasms localised within the parameningeal region and CNS infiltration].

Introduction: Solid neoplasms primarily localised within parameningeal region constitute a significant diagnostic and therapeutic problem. Solid tumours developing in the primary site are soft tissue sarcomas (STS) and lymphoepithelioma.

Aim Of Study: Evaluation of the incidence of CNS infiltration, histological type of tumour and results of treatment.

Megachemotherapy followed by autologous stem cell transplantation in children with Ewing's sarcoma.

Twenty-one children with high-risk Ewing's tumor received high-dose chemotherapy with a PBSCT. Aim of the study was evaluation of efficiency and safety of this procedure. All but three patients have meta-static disease at presentation.

Outcome of children with idiopathic thrombocytopenic purpura, based on original material.

Idiopathic or immune thrombocytopenia purpura (ITP) is a common hematologic disease in children. ITP is subdivided in an acute and chronic form based solely on the duration of thrombocytopenia. The aim of the study was to analyse the course of disease and outcome of children with acute and chronic ITP.

The radiologic diagnosis of invasive fungal infections in neutropenic children.

Fungal infections have substantially increased in incidence over the past two decades, especially among patients with cancer who have received high doses of chemotherapy. Diagnosis is based on clinical observations, radiological and laboratory methods and molecular biological techniques. Early diagnosis is important and increases overall response rates, so high-risk patients should be treated empirically, based on the clinical picture and radiologic findings alone.

Incidence of childhood cancers in rural areas of the Lublin Region in 1988-2000.

Unlabelled: The purpose of the work was the analysis of the number and structure of new neoplasm and morbidity in children living in rural areas of the Lublin Region of Poland.

Methods: the study included the population of children aged 0-17 in the years 1988-2000. The tumours were divided according to the International Classification of Childhood Cancers.

[Results of treatment for osteosarcoma in children and youth].

Bone tumours comprise about 5% of childhood neoplasms. Osteosarcoma is the most common sub-type and constitutes 60 % of all bone cancers. Incidence is similar in girls and boys and is increasing steeply with age.

[Non-Hodgkin lymphomas of the nasopharynx in children--diagnostic and therapeutic difficulties].

Unlabelled: About 7% of all childhood cancers comprise non-Hodgkin's lymphoma (NHL). NHL are heterogenous group of neoplasms deriving from lymphatic system (cell B and T). B-cell NHL characterize by high malignancy, but coincidentally good reaction for treatment.

[Central nervous system metastases in children with solid tumours].

Background: Central nervous system (CNS) metastases occur in 20-30% of adult patients with systemic cancers. but they rarely occur in children with solid tumours.

Aim: clinical and prognostic characteristics of CNS recurrence in children treated for solid tumours were analysed.

Characteristics and outcome of children with primary soft tissue sarcomas of extremities.

Objectives: To determine the characteristics and outcome or patients with primary soft tissue sarcomas of extremities in children.

Material And Methods: Thirty-six patients treated for soft tissues sarcomas were enrolled into the study. Features analysed: the incidence of soft tissues sarcoma of extremities, the time from first clinical symptoms to making the diagnosis, the primary site of tumour; histopathologic type of tumour, stage of disease, methods and results of the treatment.

[Malignant pelvic neoplasms in children treated in two Polish oncology centres].

Background: Extensive diagnostic and therapeutic dilemmas appear in children With primary malignant neoplasms located in the minor pelvis.

The Aim Of The Study: To evaluate the clinical symptoms, disease course and the results of treatment in patients with malignant pelvic neoplasms.

Material And Methods: The study included 31 children (13 boys and 18 girls; aged 2 months to 16 years; mean age -- 8 years) treated in the Departments of Paediatric Oncology and Haematology in Gdansk and Lublin during the period of 1992-2003.

Outcome of Ewing sarcoma in children and adolescents with Ewing sarcoma: a five-year survival from a single institution.

Ewing sarcoma, together with neuroblastoma and central nervous system tumors, has got the lowest percentage of complete cure among all malignant diseases in children. From 1993 to 2003, 26 patients with Ewing sarcoma were treated in Pediatric Hematology and Oncology Department, Medical University in Lublin, Poland. In this study the character and time of the clinical symptoms to making the diagnosis, the abnormalities of laboratory tests, and the primary site of tumor were analyzed.

Solid tumours of perimeningeal region in children--diagnostic and therapeutic difficulties.

Thirteen patients, aged 2-17 years, were treated because of primary solid tumours of head and neck location at the Department of Children Hematology and Oncology in Lublin. The authors analyzed clinical symptoms before diagnosis and the duration of these symptoms as well as the kind of tumours. In all cases the tumour was diagnosed on histopathological examination: soft tissue sarcomas--9 children, lymphoepithelioma--4 ones.

Primary chest tumours in children.

Primary chest tumours in children are rare and appear in 3% of cases, 83% of which are malignant. Early diagnosis is very difficult because of delayed symptoms and highly advanced stage. Symptoms of chest tumours depend on the tumour mass, localization and time of progression.

[Incidence of childhood solid tumours in Lublin region from 1988 to 2000].

The purpose of this study was the analysis of number and structure of new solid tumours and tumour morbidity among children 0-17 years old, in the Lublin Region of Poland, from 1988 to 2000. The analysis was based on sex, age and place of domicile (urban/rural region). During this time in the Lublin Region 344 cases of childhood solid tumours were reported; it was 36.