A European field assessment of the efficacy of fluralaner (Bravecto) chewable and spot-on formulations for treatment of dogs with generalized demodicosis.

Background: Recent reports indicate that the isoxazoline compounds have the potential to provide safe and effective treatment of canine generalized demodicosis, a condition that has been traditionally difficult to cure. Controlled field studies are needed to confirm this potential. A study was therefore initiated to investigate the efficacy of a single oral or spot-on treatment with fluralaner, an isoxazoline, compared with multiple topical treatments with imidacloprid-moxidectin, in dogs naturally affected by generalized demodicosis.

Diagnosis and treatment of demodicosis in dogs and cats: Clinical consensus guidelines of the World Association for Veterinary Dermatology.

Background: Demodicosis is a common disease in small animal veterinary practice worldwide with a variety of diagnostic and therapeutic options.

Objectives: To provide consensus recommendations on the diagnosis, prevention and treatment of demodicosis in dogs and cats.

Methods And Materials: The authors served as a Guideline Panel (GP) and reviewed the literature available before December 2018.