Publications by authors named "Joanna Freeman"
Article Synopsis
- Significant variability in infection control policies in the US Army's initial training led to a study focusing on COVID-19 prevention among recruits.
- Recruits were tested for COVID-19 using RT-PCR and antibody tests at specific intervals upon arrival for training, revealing a high rate of positive cases at initial testing.
- The results indicated that serological testing could enhance current methods to manage COVID-19 among new recruits, as most positive cases were identified upon arrival with no hospitalizations reported.
Background: Emerging HIV drug resistance (HIVDR) could jeopardize the success of standardized HIV management protocols in resource-limited settings. We characterized HIVDR among antiretroviral therapy (ART)-naive and experienced participants in the African Cohort Study (AFRICOS).
Methods: From January 2013 to April 2019, adults with HIV-1 RNA >1000 copies/mL underwent ART history review and HIVDR testing upon enrollment at 12 clinics in Uganda, Kenya, Tanzania, and Nigeria.
The Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 test, v2.0 (the CAP/CTM assay), was used to quantify cell-associated HIV-1 (CAH) nucleic acid in peripheral blood mononuclear cells (PBMC) from well-characterized clinical specimens from HIV-1-infected individuals on antiretroviral therapy (ART). Chronically infected individuals on ART with no detectable plasma HIV-1 RNA demonstrated average CAH burdens of 3.
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