Granulomatosis with polyangiitis (GPA) is a rare autoimmune disease characterized by necrotising granulomatous inflammation of upper and lower respiratory tract, vasculitis and glomerulonephritis. This ailment may present with cough, haemoptysis, sinusitis, nasal deformity, skin lesions, malaise, fever, anorexia, and weight loss. Oral manifestation includes strawberry gingivitis, which is a pathognomonic clinical presentation.
View Article and Find Full Text PDFAims: The purpose of the present study was to compare the effect of a new mouth wash formulation consisting of chlorhexidine and chitosan on dental plaque and its reduction to that of chlorhexidine or chitosan alone.
Materials And Methods: This study was a single-blind randomized clinical trial with a parallel group design of 3 months duration. Patients (20-40 years) who fulfilled the inclusion and exclusion criteria were assigned equally to group 1: chlorhexidine (0.
Int J Periodontics Restorative Dent
February 2020
The aim of this randomized controlled trial was to compare the clinical outcomes of modified coronally advanced tunnel technique (MCAT) with subepithelial connective tissue graft (SCTG) with and without recombinant human platelet-derived growth factor-BB (rhPDGF-BB) for mandibular multiple recessions. Twenty-four Miller Class I and III recessions were randomly assigned to a group: test (MCAT+SCTG+rhPDGF-BB) or control (MCAT+SCTG). After 6 months, mean recession-depth reduction was higher in the test group (2.
View Article and Find Full Text PDFAim: : The purpose of this trial was to evaluate the outcome of a modification of pin hole surgical technique which consists of a minimally invasive coronally advanced tunnel technique (MI-CAT) with orthodontic buttons and suturing in the treatment of multiple recession type defects.
Materials And Methods: Twelve systemically healthy patients (79 sites) aged between 22 - 55 years with Miller's Class I and II multiple recession defects were treated with minimally invasive coronally advanced tunnel technique. Thirty-nine sites were randomly assigned to a control group and the other 40 sites to the test group.
Anatomical characteristics, periodontal diseases and toothbrushing trauma make the management of multiple, adjacent, recession-type defects (MARTDs) particularly challenging. Even though connective tissue grafting is considered the gold standard in management, it has limitations, such as a second surgical site and limited amount of donor graft. Porcine pericardium membrane (PPM) is a reliable soft-tissue substitute with a three-dimensional collagen network that exhibits better stability, slow degradation, high-tear resistance, good handling properties and enhanced vascularization.
View Article and Find Full Text PDFAim: The goal of randomized controlled clinical study was to compare the clinical and radiological outcomes of the combination of Open flap debridement, Amniotic membrane and Demineralized Freeze Dried bone Allograft with Open flap debridement and Demineralized Freeze Dried bone Allograft alone in the management of periodontal intrabony defects.
Method: 10 patients with bilaterally similar intrabony defects were selected. Each of the intrabony defects were randomly allocated for control and test groups.
Neurofibromas-benign, slow-growing nerve sheath neoplasms composed of Schwann cells, perineural cells, and fibroblasts-are common neurogenic tumors on skin but uncommon intraorally. A diagnosis of neurofibroma can be established by clinical and histologic examinations. This case report describes an unusual presentation of solitary neurofibroma on the lingual gingiva of the mandibular posterior region of a 22-year-old woman.
View Article and Find Full Text PDFLow level laser has been documented in literature to promote wound healing by reducing postoperative inflammation, oedema and reduces pain. This case report demonstrates the safe and positive outcome of LLLT in conjunction with demineralised bone matrix of bovine origin in the surgical treatment of a periodontal infrabony defect. After surgical defect debridement, low level semiconductor diode laser (GaAlAr) was delivered for 5 minutes to the inner margins of flap in contact mode and the defect was irradiated with LLLT in a non-contact mode for 10 minutes.
View Article and Find Full Text PDFIntroduction: PerioChip a bovine origin gelatine based CHX chip has shown beneficial effects in the management of Chronic Periodontitis. A new fish collagen based CHX chip similar to PerioChip is currently available; however this product has not been thoroughly researched.
Aim: The aim of the present study was to evaluate the effectiveness of a new Piscean collagen-based controlled-release chlorhexidine chip (CHX chip) as an adjunctive therapy to scaling and root planing (SRP).
Background And Objectives: The purpose of this first of its kind study was to analyse the growth, development and attachment of cultured human umbilical cord stem cells alone or supplemented with basic Fibroblast Growth Factor (bFGF) on both healthy and periodontally diseased tooth surfaces in vitro.
Methods: Four groups of 12 root surface scaffolds each were classified as Group I- healthy root surfaces; Group II- periodontally diseased; Group III- Healthy with bFGF and Group IV- periodontally diseased root with bFGF. bFGF was applied in the concentration of 8 ng/ml on to the surface followed by incubation of cultured human umbilical cord stem cells (hUCMSCs) on the scaffolds.
The aim of the present study was to evaluate the influence of recombinant platelet derived growth factor-BB (rhPDGF-BB) on the cellular proliferation, morphology and adherence of human periodontal ligament fibroblasts (PLFs) to the root surfaces of periodontally diseased and healthy human teeth roots at two different time periods. Primary cell cultures of PLFs were obtained from clinically healthy premolar or mandibular third molar teeth. 11 scaffolds were prepared from healthy teeth for group-1 (Healthy Substrates), 33 scaffolds were prepared from periodontally diseased teeth, which were further divided in Group-2 - Periodontally diseased substrates, Group-3 - Scaled and Root planed (SRP) substrates, Group-4 - SRP + rhPDGF-BB (50 ng/ml).
View Article and Find Full Text PDFHistory teaches us that a great deal of effort is put forward in giving birth to a classification system, only to have it be quickly contradicted or condemned. Though we have made great strides towards the understanding of periodontitis in general, the bitter truth is that we have not hit the bull's eye on the true nature of etiopathogenesis. Until then any classification based on infectious etiology would be a misfit.
View Article and Find Full Text PDFIntroduction: Cryosurgery is a branch of therapeutics that makes use of local freezing for the controlled destruction or removal of living tissues. Cryosurgery has been tried with satisfactory results for gingival depigmentation. However, documented evidence in the literature is extremely limited.
View Article and Find Full Text PDFThe purpose of this case report is to present the results of Fibrin Adhesive System (FAS) application, a topical biological tissue adhesive in the treatment of maxillary buccal recessions. A 40-year-old male patient presented with a pair of class I buccal recession defects on maxillary cuspids. Clinical parameters were recorded at baseline, 1 month, and 3 months.
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