Publications by Joana Paula R S Yajima

Publications by authors named "Joana Paula R S Yajima"

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Metformin's performance in in vitro and in vivo genetic toxicology studies.

Juliane R Sant'Anna Joana Paula R S Yajima Lúcia J Rosada Claudinéia C S Franco Alberto J Prioli

Exp Biol Med (Maywood)

July 2013

Metformin is a hypoglycemiant drug prescribed for the treatment and control of the type 2 diabetes mellitus. Recently, the potential efficacy of this antidiabetic drug as an anticancer agent has been demonstrated in various mammalian cancer cells. This report evaluates the mutagenic as well as the recombinogenic potentials of the metformin drug in therapeutically relevant plasma concentrations (12.

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Joana Paula R S Yajima's recent research primarily focuses on the genetic toxicology of metformin, particularly its safety profile in relation to its use as a diabetes treatment and potential anticancer agent.
Her 2013 study evaluates the mutagenic and recombinogenic effects of metformin at therapeutic plasma concentrations, contributing valuable insights to its pharmacological applications.
Findings indicate that metformin's profile in both in vitro and in vivo settings reveals important implications for its use in cancer therapy, furthering understanding of its dual role as both a diabetes medication and a potential anticancer drug.

Publications by authors named "Joana Paula R S Yajima"

Metformin's performance in in vitro and in vivo genetic toxicology studies.

Synopsis of recent research by authors named "Joana Paula R S Yajima"