Publications by authors named "Joana Laranjinha"
Article Synopsis
- Cerebral aspergillosis (CA) has a high mortality rate, and the study focuses on the effectiveness and safety of isavuconazole as a treatment option compared to standard therapies like voriconazole.
- An analysis of 40 patients treated with isavuconazole across 10 countries showed that the drug effectively controlled CA in about 70-73% of cases, with a 12-week mortality rate of 18%.
- The findings suggest that isavuconazole is well-tolerated and can provide similar survival outcomes to voriconazole, making it a viable first-line treatment option for CA.
Background: Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory condition with a wide range of causes, being frequently associated with infections in adults. The association between HLH and acute HIV infection has been rarely described.
Case Presentation: A 62-year-old male, with a past medical history of Henoch-Schönlein purpura under immunosuppressive treatment, presented with a two-week history of fever, asthenia, anorexia, cough and purpuric rash.
Unlabelled: Hypereosinophilic syndrome (HES) is a heterogenous group of diseases characterized by abnormal accumulation of eosinophils in the blood or peripheral tissues. It can affect all organs and therefore clinical manifestations are highly variable. We describe the case of a 38-year-old man admitted for febrile polyserositis.
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