Dyskeratosis congenita--two siblings with a new missense mutation in the DKC1 gene.

Dyskeratosis congenital is reported in two siblings. They presented with the classic triad of mucocutaneous features: leukoplakia of the tongue, dystrophic nails, and a widespread reticulate pigmentation on the neck and upper chest. A genetic analysis was performed and a new missense mutation S356P, hemizygous, was identified in the DKC1 gene in both patients.

Regional lymphomatoid papulosis in a child--treatment with a UVB phototherapy handpiece.

Lymphomatoid papulosis (LyP) is a rare skin lymphoproliferative disorder that has been reported only rarely in children. It is included in the World Health Organization classification of cutaneous lymphomas. We report a case of LyP in a 13-year-old Caucasian girl who presented with a 6-month history of recurrent papular lesions on the left upper arm.

Letter: Association of targeted intense pulse light system UVA1-UVB and fluticasone in the treatment of vitiligo: Prospective study of 10 patients.

Vitiligo is an acquired pigmentary disorder treated frequently with PUVA and narrowband UVB phototherapy. These total body treatments are associated with side-effects in the lesional or nonlesional skin. A prospective study using a novel multiwavelength targeted Intense Pulse Light System UVA1-UVB in association with fluticasone cream was undertaken.

Treatment of Vascular Lesions of the Tongue with Nd:YAG Laser.

The treatment of vascular lesions of the tongue is a very challenging procedure since the maintenance of the lingual tissue is of critical importance. Numerous treatment options have been described in literature but the Nd:YAG Laser appears to be one of the safest therapeutic options. We described a successful treatment of vascular lesions of the tongue with an excellent clinical result after only one treatment session with the Nd:YAG laser, with conservation of the lingual tissue and its functionality.