Publications by authors named "Joana C Pinto"

Introduction: This study investigates the antecedents and consequences of strategic career management behaviours in a sample.

Methods: A total of 739 employees (Male = 442, 59.8%) with a mean age of 27.

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Introduction: In the current worldwide labor context, where a disruption took place and employees experience.

Methods: Participated in this study 739 European hybrid workers who fulfilled an online assessment protocol.

Results: Results indicate that higher ages, higher educational levels, being married, having children, working.

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Career services should be a priority for any higher education institution. These structures should be prepared to support the design, implementation, and evaluation of academic and career plans and decisions, providing services properly aligned with students' needs, preferences, and characteristics. The present study addressed these questions by analyzing data from an online survey administered to 361 Portuguese higher education students.

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Von Willebrand disease (VWD) is the most frequent inherited bleeding disorder caused by quantitative or qualitative defects of von Willebrand factor (VWF). This protein far from simplicity constitutes a very complex molecular model, remaining unravelled yet many aspects of it, even though the VWF gene (VWF) was cloned already in 1985 and the structure of VWF well defined. VWD diagnosis is difficult to achieve in a significant proportion of patients due to both disease heterogeneity and limitations in existing test processes.

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Introduction: Type 2N von Willebrand disease (VWD) is characterized by a decreased affinity of von Willebrand factor (VWF) for factor VIII (FVIII). Abnormal binding of FVIII to VWF (VWF:FVIIIB), results in low FVIII plasma levels, which can lead to a misdiagnosis of mild haemophilia A. Accurate diagnosis of type 2N VWD is essential for appropriate genetic counselling and therapy.

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Objectives: We investigated the frequency distribution and haplotype diversity of human African trypanosomiasis (HAT) resistance and lactase persistence (LP) variants in populations from the Angolan Namib to trace the spread of these genetic adaptations into southwestern Africa.

Materials And Methods: We resequenced two fragments of the LCT enhancer and the APOL1 gene and genotyped flanking short tandem repeat loci in six groups with different subsistence traditions living in the Angolan Namib, and in a comparative dataset including other populations from Africa and Europe. LP in the Angolan Namib is represented by the -14010*C allele, which is associated with a predominant haplotype that is shared with other southern and eastern African populations.

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Objectives: The present study aims to test the factor structure of two sleep questionnaires and their internal consistency in a sample of adolescents and their respective parents and to evaluate the validity and robustness of a three-dimensional model about sleep, addressing nine subcategories related to sleep habits, personal and environmental factors.

Methods: Participants were 654 adolescents from Portuguese schools, who completed "My Sleep and I" questionnaire, and 664 parents who completed "My child׳s sleep" questionnaire; to them confirmatory factor analysis was applied.

Results: Confirmatory factor analysis indicate that a nine-factor model has better fit indices compared with the others tested models for both samples (adolescents: χ (2)/df (Chi-square/degrees of freedom)=2.

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The correct diagnosis and classification of Von Willebrand disease (VWD) is important for therapy and genetic counseling but is made difficult due to the variability of its clinical expression and limitations of laboratory methods. A national registry of VWD patients has been initiated in Spain. The results of a concise survey on the diagnosis of VWD show the frequency of VWD is fivefold greater in Spain than that expected from epidemiological studies in other European countries; this may result from overdiagnosis and/or a higher prevalence of VWD.

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Background: Of patients with severe aortic stenosis, 15-25% present with bleeding episodes possibly attributable to acquired von Willebrand syndrome (AVWS). AVWS associated with mitral valve prosthesis leakage has not been reported.

Methods And Results: Five patients receiving appropriate oral anticoagulation showed mitral valve prosthesis leakage and bleeding episodes; all of them required hospitalization and two blood transfusions, and a von Willebrand factor (VWF) analysis was performed.

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Purpose: To characterize the reading ability of children with five years of education according to temporal standards, as well as to compare the reading fluency performance of these children before and after a reading program based on prosody standards.

Methods: Thirty two fourth-grade children participated in this study. They performed reading aloud and picture description tasks in order to verify reading rate, speech rate, text comprehension and the adequacy of prosody variation.

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