The use of algeness in the face and neck: a safe, alternative filler for cosmetics and reconstruction.

Background: The search for effectiveness and safety in the use of dermal fillers, is an ongoing challenge for aesthetic physicians, plastic surgeons and the science of bioengineering. Understanding the variety of characteristics, capabilities, advantages and disadvantages of available injectables is essential to reduce complication rates and achieve satisfying aesthetic and functional results.

Methods: Algeness is a 100% natural, biodegradable tissue implant, consisting of a gel derived from agarose.

Spreading Pattern and Tissue Response to Hyaluronic Acid Gel Injections in the Subcutis: Ultrasound Videos, Ultrasound Measurements, and Histology.

Background: Despite the popularity of hyaluronic acid (HA) filler treatments, few publications focus on their effects on adipose tissue.

Objectives: The authors assessed the deposition pattern in the subcutis of injected HA, the tissue response at short and intermediate term, and the effects of remodeling the filler by strong finger pressure immediately after the treatment.

Methods: Two brands, specifically developed by the industry for deep injection, were compared.

Real-world Experience with Volume Augmentation using Cohesive Polydensified Matrix Hyaluronic Acid Gel: A Retrospective Single-center Analysis of 110 Consecutive Patients with Medium- to Long-term Follow-up.

Hyaluronic acid (HA) volumizer injection into subcutaneous and deep tissue layers is increasingly used for nonsurgical volume loss correction. Information on optimal techniques, safety, and medium- to long-term satisfaction is limited. This study evaluated cohesive polydensified matrix HA volumizer CPM-26 (Modélis Shape or Belotero Volume) across different indications.

Ultrasound and Histologic Examination after Subcutaneous Injection of Two Volumizing Hyaluronic Acid Fillers: A Preliminary Study.

Background: This study examined the influence of hyaluronic acid (HA) crosslinking technology on the ultrasound and histologic behavior of HA fillers designed for subcutaneous injection.

Methods: One subject received subcutaneous injections of 0.25 ml Cohesive Polydensified Matrix (CPM) and Vycross volumizing HA in tissue scheduled for abdominoplasty by bolus and retrograde fanning techniques.

Treatment of Age-related Mid-face Atrophy by Injection of Cohesive Polydensified Matrix Hyaluronic Acid Volumizer.

Objective: Cohesive Polydensified Matrix® Hyaluronic Acid Volumizer is designed to be injected subcutaneously or in deeper soft tissue layers to restore facial volumes. This post-marketing clinical follow-up was performed to confirm the safety and effectiveness of the product up to 18 months.

Design: Injections were performed according to standard clinical practice and patients were followed-up at Months 1, 3, 6, 9, 12, and optionally at Month 18.