Publications by authors named "Joan Powling"

Article Synopsis
  • Multidrug-resistant (MDR) typhoid, caused by a specific lineage of Salmonella called H58, has spread rapidly across Asia and Africa over the past 30 years, posing a significant global health threat.
  • The research reveals that H58 is displacing antibiotic-sensitive strains and is linked to numerous transmissions, including ongoing MDR epidemics within Africa.
  • The study highlights the genetic characteristics of the H58 lineage, providing insights that can help manage MDR typhoid and similar antibiotic-resistant bacteria globally.
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Objectives: To determine incidence and trends in antibiotic resistance in Australian Salmonella enterica subspecies enterica serovars Typhi (S. Typhi) and Paratyphi (S. Paratyphi) isolates over the past 26 years.

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A national scheme of Salmonella surveillance emerged in Australia as a direct result of high-profile outbreaks in 1977. A typing laboratory in Victoria put together a working model using the computer technology available at the time. The evolving information-gathering system has stood the test of time and has provided an invaluable bank of information covering isolations from humans and other sources.

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