Synopsis of recent research by authors named "Joan Paterson"
- Joan Paterson's recent research primarily focuses on the genetic predisposition to various types of cancer, particularly breast and ovarian cancers, and the implications of inherited genetic mutations in cancer risk.
- Key findings include the identification of multiple deleterious variants from whole-genome sequencing in cancer-predisposition genes among individuals with multiple primary tumors, as well as significant associations between genetic variants and breast cancer risk in BRCA1 and BRCA2 mutation carriers.
- Paterson's work also emphasizes the importance of understanding gene interactions and common susceptibility alleles that modify cancer risk, contributing to the fields of cancer genomics and hereditary cancer syndromes.
