Renal replacement therapy in Europe: a summary of the 2012 ERA-EDTA Registry Annual Report.

Background: This article summarizes the 2012 European Renal Association-European Dialysis and Transplant Association Registry Annual Report (available at www.era-edta-reg.org) with a specific focus on older patients (defined as ≥65 years).

Prevalence and clinical characteristics of renal transplant patients with true resistant hypertension.

Objective: Arterial hypertension is a prevalent complication that occurs in 75-90% of kidney-transplant recipients. Data about resistant arterial hypertension are scarce. The aim of this multicenter, cross-sectional, and observational study was to assess the prevalence and the clinical features of true resistant hypertension among renal-transplant patients.

Renal sodium transporters are increased in urinary exosomes of cyclosporine-treated kidney transplant patients.

Background/aims: Cyclosporine (CsA) is a calcineurin inhibitor widely used as an immunosuppressant in organ transplantation. Previous studies demonstrated the relationship between CsA and renal sodium transporters such as the Na-K-2Cl cotransporter in the loop of Henle (NKCC2). Experimental models of CsA-induced hypertension have shown an increase in renal NKCC2.

Is it appropriate to implant kidneys from elderly donors in young recipients?

Background: Kidneys from elderly donors tend to be implanted in recipients who are also elderly. We present the results obtained after 10 years of evolution on transplanting elderly kidneys into young recipients.

Methods: Ninety-one consecutive transplants are studied, carried out in our center with kidneys from cadaver donors older than 60 years implanted in recipients younger than 60 years.

Aortofemoral bypass to bridge end-stage renal disease patients with severe iliac calcification to kidney transplantation.

Patients undergoing hemodialysis have a lower survival rate than those who receive a kidney transplant. Mortality among hemodialysis patients is approximately 14.5% compared with 1.

Tacrolimus/mycophenolate mofetil-based immunosuppression in aged kidney transplant. A prospective study.

Background: At the moment, controversy has arisen about immunosuppression in aged kidney transplant recipients. We present our results on the efficacy and safety of induction treatment based on tacrolimus (FK506) and mycophenolate mofetil (MMF).

Material And Method: We performed 72 transplants in patients of 60 years or older.