Longitudinal deep learning clustering of Type 2 Diabetes Mellitus trajectories using routinely collected health records.

Type 2 diabetes mellitus (T2DM) is a highly heterogeneous chronic disease with different pathophysiological and genetic characteristics affecting its progression, associated complications and response to therapies. The advances in deep learning (DL) techniques and the availability of a large amount of healthcare data allow us to investigate T2DM characteristics and evolution with a completely new approach, studying common disease trajectories rather than cross sectional values. We used an Kernelized-AutoEncoder algorithm to map 5 years of data of 11,028 subjects diagnosed with T2DM in a latent space that embedded similarities and differences between patients in terms of the evolution of the disease.

Acoustic and prosodic information for home monitoring of bipolar disorder.

Epidemiological studies suggest that bipolar disorder has a prevalence of about 1% in European countries, becoming one of the most disabling illnesses in working age adults, and often long-term and persistent with complex management and treatment. Therefore, the capacity of home monitoring for patients with this disorder is crucial for their quality of life. The current paper introduces the use of speech-based information as an easy-to-record, ubiquitous and non-intrusive health sensor suitable for home monitoring, and its application in the framework on the NYMPHA-MD project.