Publications by authors named "Joan E Panke"

The S3-guideline on endometrial cancer, first published in April 2018, was reviewed in its entirety between April 2020 and January 2022 and updated. The review was carried out at the request of German Cancer Aid as part of the Oncology Guidelines Program and the lead coordinators were the German Society for Gynecology and Obstetrics (DGGG), the Gynecology Oncology Working Group (AGO) of the German Cancer Society (DKG) and the German Cancer Aid (DKH). The guideline update was based on a systematic search and assessment of the literature published between 2016 and 2020.

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Article Synopsis
  • - The S3-guideline for endometrial cancer, initially released in April 2018, underwent a comprehensive review and update from April 2020 to January 2022, as requested by German Cancer Aid and coordinated by prominent gynecological and oncology organizations in Germany.
  • - The update focused on integrating new evidence and refining recommendations to enhance treatment approaches, emphasizing personalized therapies to minimize unnecessary radical surgeries and non-beneficial adjuvant treatments for low-risk patients.
  • - The revised guideline aims to optimize care for high-risk patients by clarifying the roles of radical surgery and additional treatments, ultimately improving survival rates and quality of life, while serving as a foundation for certified gynecological cancer centers.
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Article Synopsis
  • The first German interdisciplinary S3-guideline for diagnosing and treating endometrial cancer was introduced in April 2018, with funding from German Cancer Aid and coordination by major gynecological organizations.
  • It emphasizes evidence-based, risk-adapted treatment strategies that can minimize unnecessary surgery and chemotherapy for low-risk patients, ultimately improving their quality of life and reducing healthcare costs.
  • For high-risk patients, the guideline outlines the best strategies for surgical intervention and additional therapies, aiming to enhance survival rates and ensure that quality indicators influence the certification of gynecological cancer centers.
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The first German interdisciplinary S3-guideline on the diagnosis, therapy and follow-up of patients with endometrial cancer was published in April 2018. Funded by German Cancer Aid as part of an Oncology Guidelines Program, the lead coordinators of the guideline were the German Society of Gynecology and Obstetrics (DGGG) and the Gynecological Oncology Working Group (AGO) of the German Cancer Society (DKG). The use of evidence-based, risk-adapted therapy to treat low-risk women with endometrial cancer avoids unnecessarily radical surgery and non-useful adjuvant radiotherapy and/or chemotherapy.

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Aim: After radical prostatectomy, PSA levels that reach near zero values in less than 14 days are associated with a favourable prognosis. The aim of this analysis was to investigate whether PSA also declines to near zero values after combined tele-brachytherapy.

Materials And Methods: Forty-one patient, treated with combined tele-brachytherapy for prostate cancer, were followed for at least 2 years after treatment with repeated PSA measurements.

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Background And Purpose: For ruthenium plaque therapy of uveal melanoma the precise knowledge of the tumor height is necessary. The purpose of this analysis is to examine systematic differences between ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) measurements of tumor height in uveal melanoma.

Material And Methods: From 1993 to 2000, 208 patients with uveal melanoma were treated with ruthenium therapy.

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Purpose: To evaluate the frequency and amount of displacements after repositioning a patient on the physical simulator following virtual simulation.

Material And Methods: After laser marking at the CT scanner and virtual simulation, patients were repositioned on the simulator. The isocenter obtained from the calculated table movements was checked by fluoroscopically measuring the distances to standardized anatomic landmarks and comparing them to the treatment plan.

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