Rates of New Peanut Allergy and Discontinuation Following Introduction in High-Risk Infants.

Background: Peanut introduction guidelines recommend that infants with severe eczema and/or egg allergy consume 6 g of peanut protein weekly to prevent peanut allergy. Rates of new peanut allergy after introduction and adherence remain under study.

Objective: To determine compliance with peanut introduction guidelines, rates of new peanut allergy, and reasons for discontinuation of peanut consumption in a cohort of high-risk infants.

Home Introduction of Baked Egg After Oral Food Challenge.

Background: Baked egg (BE) introduction may accelerate resolution of egg allergy. Long-term data regarding the safety and success of BE introduction in the real world are limited.

Objective: To identify predictors of future egg consumption and barriers to advancement based on characteristics during and after BE oral food challenges (OFCs).

Efficacy and safety of baked milk oral immunotherapy in children with severe milk allergy: A randomized, double-blind, placebo-controlled phase 2 trial.

Background: Cow's milk allergy is the most common food allergy in young children and has no current treatment. Oral immunotherapy studies to date have shown efficacy but high rates of adverse reactions.

Objective: We sought to evaluate the safety and efficacy of baked milk oral immunotherapy (BMOIT) in children allergic to baked milk.

Ara h 2-specific IgE is superior to whole peanut extract-based serology or skin prick test for diagnosis of peanut allergy in infancy.

Background: Screening of high-risk infants for peanut allergy (PA) before introduction is now recommended in the United States, but the optimal approach is not clear.

Objective: We sought to compare the diagnostic test characteristics of peanut skin prick test (SPT), peanut-specific IgE (sIgE), and sIgE to peanut components in a screening population of infants before known peanut exposure.

Methods: Infants aged 4 to 11 months with (1) no history of peanut ingestion, testing, or reaction and (2) (a) moderate-severe eczema, (b) history of food allergy, and/or (c) first-degree relative with a history of PA received peanut SPT, peanut-sIgE and component-IgE testing, and, depending on SPT wheal size, oral food challenge or observed feeding.

Oral immunotherapy for treatment of peanut allergy.

The US Food and Drug Administration's approval of a peanut oral immunotherapy product in January 2020 is a landmark development in the field of food allergy therapy. While food allergy prevalence has been increasing, this product is the first approved therapy for food allergy. Oral immunotherapy has many similarities to subcutaneous immunotherapy and drug desensitization protocols, but does not lead to sustained unresponsiveness.

Long-Term Follow-Up After Baked Milk Introduction.

Background: Clinical trials of baked milk (BM) introduction have demonstrated accelerated resolution of milk allergy.

Objective: Long-term data regarding real-world introduction of BM are lacking. We sought to characterize our experience of BM introduction.

Epidemiology of Food Allergy.

Understanding the epidemiology of food allergy is complicated by the difficulty of identifying it on a large scale. The prevalence of food allergy is higher in younger age groups and decreases with age. Allergy to peanut and egg seems to be more common in Northern Europe, the United States, Canada and Australia compared with Southern Europe, Eastern Europe and Asia, whereas shellfish and fish allergies may be more common in Asia.

Allergic Rhinitis: Environmental Determinants.

The increasing prevalence of allergic rhinitis (AR) seems to be linked to several important environmental factors that interact with underlying genetic predisposition to influence the risk of this disease. This article examines these environmental determinants of AR, and the evidence for their association with disease prevalence. Exposure to a variety of aeroallergens is strongly implicated in the pathogenesis and progression of AR.

Incidental renal mass found on focused assessment with sonography in trauma.

We present the case of a 9-year-old female who presented after minor blunt abdominal trauma during a sporting event. On focused assessment with sonography for trauma, she was found to have an incidental renal mass, which was ultimately diagnosed as a renal cell carcinoma. In this report, we focus on the use of bedside ultrasound as a screening test and the management of incidental findings.