Person-centred care provided by a multidisciplinary primary care team to improve therapeutic adequacy in polymedicated elderly patients (PCMR): randomised controlled trial protocol.

Introduction: The increase in elderly population has led to an associated increase in multiple pathologies, frailty, polypharmacy, healthcare costs, decreased quality of life and mortality. We designed an intervention based on person-centred care model. This article outlines a study protocol, which aims to explore the effects of the intervention to improve therapeutic adequacy in polymedicated elderly patients.

Distribution of dissolved organic matter in freshwaters using excitation emission fluorescence and Multivariate Curve Resolution.

Multivariate Curve Resolution Alternating Least Squares (MCR-ALS) method with the trilinearity constraint is proposed for the analysis of excitation-emission fluorescence data from Dissolved Organic Matter (DOM) in fresh water natural systems, and the results obtained are compared with those obtained with PARAFAC. The effects of different number of components and constraints on the stability of the proposed models are compared. MCR-ALS is shown to be an effective way to characterize and resolve DOM sources in natural fresh water systems from EEM data, with good correlation with experimentally measured DOM concentration values.

Exploring the links between antibiotic occurrence, antibiotic resistance, and bacterial communities in water supply reservoirs.

Antibiotic resistance represents a growing global health concern due to the overuse and misuse of antibiotics. There is, however, little information about how the selective pressure of clinical antibiotic usage can affect environmental communities in aquatic ecosystems and which bacterial groups might be responsible for dissemination of antibiotic resistance genes (ARGs) into the environment. In this study, chemical and biological characterization of water and sediments from three water supply reservoirs subjected to a wide pollution gradient allowed to draw an accurate picture of the concentration of antibiotics and prevalence of ARGs, in order to evaluate the potential role of ARGs in shaping bacterial communities, and to identify the bacterial groups most probably carrying and disseminating ARGs.

Elastofibroma dorsi: an uncommon and under-diagnosed tumour.

Elastofibroma dorsi is a relatively rare soft-tissue tumour localized at the infra-scapular level and/or subscapular regions. It usually occurs between the fourth and seventh decade of life, and is more common in females. We reviewed sixteen elastofibromas diagnosed in 12 patients (7 females, 58.

Driving factors of the phytoplankton functional groups in a deep Mediterranean reservoir.

The control of phytoplankton growth is mainly related to the availability of light and nutrients. Both may select phytoplankton species, but only if they occur in limiting amounts. During the last decade, the functional groups approach, based on the physiological, morphological and ecological attributes of the species, has proved to be a more efficient way to analyze seasonal changes in phytoplankton biomass.

Tailoring dam structures to water quality predictions in new reservoir projects: assisting decision-making using numerical modeling.

Selection of reservoir location, the floodable basin forest handling, and the design of dam structures devoted to water supply (e.g. water outlets) constitute relevant features which strongly determine water quality and frequently demand management strategies to be adopted.