Physical activity and anxiety during the COVID-19 pandemic in Tanzania: insights for public health policy in low-income contexts.

Background: The COVID-19 pandemic heightened anxiety levels globally, disproportionately affecting low-and middle-income countries (LMICs). Physical activity (PA) has shown potential to alleviate mental health challenges, including anxiety. This study explores the relationship between PA and anxiety among Tanzanian adults during the pandemic, examining whether self-reported health status moderates this relationship and identifying demographic variations.

"Good fathers": Community perceptions of idealized fatherhood and reported fathering behaviors in Mwanza, Tanzania.

Globally, perceptions of idealized fatherhood have been expanding beyond men's breadwinning roles to also value men's engagement in nurturing care. While fathers' caregiving behaviors are increasing, most childcare activities are still largely performed by mothers. In this study, we unpacked community members' beliefs about the meaning of "good fathers" and explored the degree to which these values aligned with the main caregiving behaviors reported about fathers with young children under age 2 years in Mwanza, Tanzania.

: Women's economic empowerment and family caregiving dynamics in Tanzania.

Women's economic empowerment is recognized as a fundamental component of gender equality and global development. Despite a significant body of evidence highlighting the positive effects of women's labor force participation in low- and middle-income countries, relatively few studies have explored how caregivers of young children perceive women's economic empowerment in relation to childcare and family responsibilities. The objective of this study was to examine how mothers and fathers viewed the links between maternal employment and family caregiving dynamics specifically in terms of couples' relationships and parenting.

Self-perception of health and physical activity levels among the youth and adults before and amidst the COVID-19 pandemic.

Background: Emerging research indicates that the COVID-19 pandemic and associated restrictions led to decreased physical activity levels and poorer health globally. However, most studies on this topic have focused on advanced countries, leaving a gap in understanding the impact in countries like Ghana. This study aimed to fill this gap by assessing self-perceived health status and physical activity levels among youth and adults in Ghana before, during, and after the COVID-19 restrictions.

Validating the efficacy and value proposition of mental fitness vocal biomarkers in a psychiatric population: prospective cohort study.

Background: The utility of vocal biomarkers for mental health assessment has gained increasing attention. This study aims to further this line of research by introducing a novel vocal scoring system designed to provide mental fitness tracking insights to users in real-world settings.

Methods: A prospective cohort study with 104 outpatient psychiatric participants was conducted to validate the "Mental Fitness Vocal Biomarker" (MFVB) score.

Fathers' mental health and coping strategies: a qualitative study in Mwanza, Tanzania.

Objectives: To investigate the nature of paternal mental health problems, their causes and the coping strategies used by fathers of young children under the age of 2 years.

Design And Setting: We conducted in-depth interviews with fathers, mothers, community leaders and community health workers as well as focus group discussions with fathers-only, mothers-only and mixed groups of fathers and mothers. Respondents provided their perspectives on the psychosocial challenges affecting fathers and how fathers responded to their mental health problems.

Leucine Supplementation Improves Diastolic Function in HFpEF by HDAC4 Inhibition.

Heart failure with preserved ejection fraction (HFpEF) is a complex syndrome associated with a high morbidity and mortality rate. Leucine supplementation has been demonstrated to attenuate cardiac dysfunction in animal models of cachexia and heart failure with reduced ejection fraction (HFrEF). So far, no data exist on leucine supplementation on cardiac function in HFpEF.

Formative research to inform the future design of a multicomponent fatherhood intervention to improve early child development in Mwanza, Tanzania.

Fathers can influence child development through various pathways, such as via their caregiving behaviors, marital relationships, and their psychosocial wellbeing. However, few parenting interventions have been designed to target these multiple dimensions among fathers with young children in low- and middle-income countries. In June 2022, we conducted qualitative formative research to explore the perceptions surrounding fatherhood and the underlying barriers and enablers to engaged fathering in Mwanza, Tanzania.

Depression Classification Using n-Gram Speech Errors from Manual and Automatic Stroop Color Test Transcripts.

While the psychological Stroop color test has frequently been used to analyze response delays in temporal cognitive processing, minimal research has examined incorrect/correct verbal test response pattern differences exhibited in healthy control and clinically depressed populations. Further, the development of speech error features with an emphasis on sequential Stroop test responses has been unexplored for automatic depression classification. In this study which uses speech recorded via a smart device, an analysis of и-gram error sequence distributions shows that participants with clinical depression produce more Stroop color test errors, especially sequential errors, than the healthy controls.

Automatic Detection of COVID-19 Based on Short-Duration Acoustic Smartphone Speech Analysis.

Currently, there is an increasing global need for COVID-19 screening to help reduce the rate of infection and at-risk patient workload at hospitals. Smartphone-based screening for COVID-19 along with other respiratory illnesses offers excellent potential due to its rapid-rollout remote platform, user convenience, symptom tracking, comparatively low cost, and prompt result processing timeframe. In particular, speech-based analysis embedded in smartphone app technology can measure physiological effects relevant to COVID-19 screening that are not yet digitally available at scale in the healthcare field.

Wound cleansing: benefits of hypochlorous acid.

Cleansing provides an opportunity to remove pathogens from the wound bed, thereby preventing an increase in the bioburden and delayed healing. This article describes the reported efficacy of hypochlorous acid-containing wound cleansers.

Performance of a factory-calibrated, real-time continuous glucose monitoring system during elective abdominal surgery.

We assessed the performance of the factory-calibrated, sixth-generation continuous glucose monitoring (CGM) system Dexcom G6® (DexCom Inc., San Diego, California) during elective abdominal surgery. Twenty adults with (pre)diabetes undergoing abdominal surgery (>2 hours; 15 men, age 69 ± 13 years, glycated haemoglobin 53 ± 14 mmol/mol) wore the sensor from 1 week prior to surgery until hospital discharge.

Loss of Sox9 in cardiomyocytes delays the onset of cardiac hypertrophy and fibrosis.

Background: The transcription factor Sox9 has been associated with cardiac injury and remodeling. Studies of mammalian hearts confirm Sox9 upregulation in fibroblasts following ischemic insults associated with enhanced fibrosis. The role of cardiomyocyte-specific Sox9 remains unclear.

Inhibition of anti-apoptotic signals by Wortmannin induces apoptosis in the remote myocardium after LAD ligation: evidence for a protein kinase C-δ-dependent pathway.

It has been shown that, in the remote myocardium after infarction (MI), protein kinase C (PKC) inhibition reduces apoptosis both by blocking proapoptotic pathways and by activating antiapoptotic signals including the Akt pathway. However, it was open if vice versa, blockade of antiapoptotic pathways may influence proapoptotic signals. To clarify this, the present study tested the effects of the PI3-kinase blocker Wortmannin on proapoptotic signals and on apoptosis execution in the remote myocardium after infarction.

Stimulation of adenosine A2b receptors blocks apoptosis in the non-infarcted myocardium even when administered after the onset of infarction.

Objective: Chronic adenosine A2b receptor stimulation has been shown to prevent ventricular remodelling after myocardial infarction (MI). We hypothesized that this effect is due to the inhibition of cardiac myocyte apoptosis in the myocardium remote from the infarction.

Methods: Rats were subjected to MI by LAD ligation in situ.

On the use of cellular telephony for audio interaction with animals.

Playback is an important method of surveying animals, assessing habitats and studying animal communication. However, conventional playback methods require on-site observers and therefore become labour-intensive when covering large areas. Such limitations could be circumvented by the use of cellular telephony, a ubiquitous technology with increasing biological applications.

Distribution of inorganic and methylmercury among tissues in mink (Mustela vison) and otter (Lutra canadensis).

Total mercury and methylmercury concentrations were measured in brain, kidney, liver, and fur from several mink and otter collected in south-central Ontario. There was a large range in concentrations of both total and methylmercury. The percentage of the total mercury present as methylmercury varied among the various tissues; however, the percentage mercury found as the methyl form was relatively constant within a given tissue for all tissues in mink but highly variable in otter.

The effect of fat and carbohydrate content of the diet on voluntary ethanol intake in golden hamsters.

Golden hamsters, which avidly consume ethanol solutions, had continuous access to food and water and to either 15% or 30% ethanol solution (v/v) over a period of weeks. Hamsters consumed approximately equal amounts of absolute ethanol when maintained on either a Purina Chow diet or a high-carbohydrate, low-fat diet (7.6 and 7.

An examination of spatial variation in mercury concentrations in otter (Lutra canadensis) in south-central Ontario.

Hair samples were collected from otter (Lutra canadensis) trapped in several parts of south-central Ontario, Canada. The concentrations of total Hg in hair were compared with methyl mercury concentrations in liver tissues from the same individuals to determine if hair is a suitable monitoring tissue. Hg in the two tissues was significantly correlated.

Dietary energy shortage and ethanol intake in golden hamsters.

Adult male golden hamsters, which are avid consumers of ethanol solutions, were maintained on powdered Purina chow and tap water, and they were permitted continuous access to either a 15% or a 30% ethanol solution (v/v). In two experiments, the effect of chronic dietary energy shortage on ethanol consumption was examined. Energy shortage was produced either by food restriction (Experiment 1) or by dilution of the diet with nonnutritive cellulose (Experiment 2).

Genotype and anesthetic determine mate choice in Drosophila melanogaster.

Genetic differences that influence mating preferences were studied in genetically defined lines of Drosophila melanogaster. Initial results suggested substantial differences between two types of females with respect to the types of male preferred as mates, but further experimentation showed that the mating patterns were conditional on the mode of anesthesia (CO2 versus ether). In a statistical test of independence, the major determinant of mating choice in these experiments was due to an interaction effect between genotypes and mode of anesthesia.

Parasites of moose (Alces alces) from an agricultural area of eastern Ontario.

Viscera of 16 moose and hide samples of 24 moose (Alces alces) shot in eastern Ontario in 1985 were examined for parasites. Two species of trematodes, one species of cestode, five species of nematodes and one species of tick were recovered. One nematode species, Trichuris discolor, is reported for the first time from moose.