Publications by authors named "Joabi Rocha Nascimento"
Prevalence of glucose 6-phosphate dehydrogenase deficiency in highly malaria-endemic municipalities in the Brazilian Amazon: A region-wide screening study.
Joabi Rocha Nascimento Jose Diego Brito-Sousa Anne Cristine Gomes Almeida Marly M Melo Monica Regina Farias Costa
Lancet Reg Health Am
August 2022
Article Synopsis
- Difficulties in assessing glucose-6-phosphate dehydrogenase deficiency (G6PDd) in remote areas pose risks for safely using malaria treatments like primaquine and tafenoquine, due to potential hemolysis.
- A study conducted in the Brazilian Amazon from 2014 to 2018 screened nearly 15,000 males for G6PDd, revealing a 5.6% prevalence overall, with the highest rates in Acre and Amapá.
- The findings suggest that many individuals could suffer hemolysis if treated with certain anti-malarial drugs, highlighting the need for G6PDd screening to protect patients and support malaria elimination efforts.