Anterograde-propagation of axonal degeneration in the visual system of wlds mice characterized by diffusion tensor imaging.

Purpose: To evaluate the feasibility of using diffusion tensor imaging (DTI) to characterize the temporospatial profile of axonal degeneration and its relation to blood-brain barrier (BBB) permeability.

Materials And Methods: Longitudinal DTI was performed in Wallerian degeneration slow (WldS) mice following retinal ischemia. In parallel, gadolinium (Gd)-enhanced T -weighted imaging (Gd-T WI) was performed to evaluate BBB permeability in white matter during axonal degeneration.

Tell me about Pangolins! Evidence that children are motivated to learn about kinds.

We propose that conceptual development is facilitated by an early emerging bias that leads children to privilege learning about kinds of things in the world (e.g., dogs, chairs).