The ability to manufacture 3D metallic architectures with microscale resolution is greatly pursued because of their diverse applications in microelectromechanical systems (MEMS) including microelectronics, mechanical metamaterials, and biomedical devices. However, the well-developed photolithography and emerging metal additive manufacturing technologies have limited abilities in manufacturing micro-scaled metallic structures with freeform 3D geometries. Here, for the first time, the high-fidelity fabrication of arbitrary metallic motifs with sub-10 µm resolution is achieved by employing an embedded-writing embedded-sintering (EWES) process.
View Article and Find Full Text PDFAims: This study aimed to construct a nomogram for predicting the risk of cognitive frailty in patients on maintenance haemodialysis.
Design: An explorative cross-sectional design was adopted.
Methods: From April 2022 to July 2022, 496 participants were recruited from five haemodialysis centres in Qingdao, Shandong Province, China.
The aim of this experiment is to evaluate the effects of adding porous zinc oxide, plant polyphenols, and their combination to diets without antibiotics and high-dose zinc oxide on the growth performance, diarrhea incidence, intestinal morphology, and microbial diversity of weaned piglets. A total of 150 Duroc × Landrace × Large White weaned piglets were allocated to one of five diets in a randomized complete block design with six replicates and five piglets per replicate. The experimental period was 42 d, divided into two feeding stages: pre-starter (0-14 d) and starter (14-42 d).
View Article and Find Full Text PDFThe interplay between protein folding and biological activity is crucial, with the integrity of the proteome being paramount to ensuring effective biological function execution. In this study, we report a dual-environment-sensitive probe A1, capable of selectively binding to protein aggregates and dynamically monitoring their formation and degradation. Through , cellular, and tissue assays, A1 demonstrated specificity in distinguishing aggregated from folded protein states, selectively partitioning into aggregated proteins.
View Article and Find Full Text PDFWhile deep learning has found widespread utility in gearbox fault diagnosis, its direct application to wind turbine gearboxes encounters significant hurdles. Disparities in data distribution across a spectrum of operating conditions for wind turbines result in a marked decrease in diagnostic accuracy. In response, this study introduces a tailored dynamic conditional adversarial domain adaptation model for fault diagnosis in wind turbine gearboxes amidst cross-condition scenarios.
View Article and Find Full Text PDFACS Appl Mater Interfaces
November 2023
Poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS), a prominent conducting polymer, holds significance in both industry and academia. However, prevailing fabrication techniques struggle to build spanning features of PEDOT:PSS with both high electrical conductivity and fine resolution due to layerwise assembly in the plane. Here, we report an "omnidirectional printing and secondary doping" strategy to construct spanning, filamentary and out-of-plane 3D PEDOT:PSS with high conductivity.
View Article and Find Full Text PDFObjective: To obtain high-purity nasal epithelial cells (NEC) while avoiding the irritation experienced by patients during nasal biopsies.
Methods: This prospective, observational study enrolled patients undergoing surgical treatment for nasal septum deviation. After general anaesthesia, a novel nasal scraping spoon was used to collect epithelial cells from the mid-part of the inferior turbinate.
Higher standards for reliability and efficiency apply to the connection between vehicle terminals and infrastructure by the fifth-generation mobile communication technology (5G). A vehicle-to-infrastructure system uses a communication system called NR-V2I (New Radio-Vehicle to Infrastructure), which uses Link Adaptation (LA) technology to communicate in constantly changing V2I to increase the efficacy and reliability of V2I information transmission. This paper proposes a Double Deep Q-learning (DDQL) LA scheduling algorithm for optimizing the modulation and coding scheme (MCS) of autonomous driving vehicles in V2I communication.
View Article and Find Full Text PDFBackground: Job performance is known as an essential reflection of nursing quality. Colleague solidarity, positive emotion, and turnover intention play effective roles in a clinical working environment, but their impacts on job performance are unclear. Investigating the association between nurses' colleague solidarity and job performance may be valuable, both directly and through the mediating roles of positive emotion and turnover intention.
View Article and Find Full Text PDFThree-dimensional-structured metal oxides have myriad applications for optoelectronic devices. Comparing to conventional lithography-based manufacturing methods which face significant challenges for 3D device architectures, additive manufacturing approaches such as direct ink writing offer convenient, on-demand manufacturing of 3D oxides with high resolutions down to sub-micrometer scales. However, the lack of a universal ink design strategy greatly limits the choices of printable oxides.
View Article and Find Full Text PDFAim: The present study aimed to develop the Risk Perception Scale of Disease Aggravation for older patients with non-communicable diseases and evaluate its psychometric properties.
Design: Instrument development and cross-sectional validation study were conducted.
Methods: This study contained four phases.
Research (Wash D C)
April 2023
Soft pneumatic actuators (SPAs) have attracted enormous attention in the growing field of robotics. Among different SPAs, composite reinforced actuators (CRAs) are widely used because of their simple structure and high controllability. However, multistep molding, a time-consuming method, is still the predominant fabrication method.
View Article and Find Full Text PDFBackground: In the nasal cavity, nitric oxide (NO) is involved in many physiological functions, including antibacterial and antiviral activity, promotion of nasal mucociliary clearance, and regulation of blood vessel expansion in the nasal mucosa. We investigated the distribution of NO concentration in the nasal cavity of healthy individuals during breathing.
Methods: A three-dimensional numerical model of the nasal airway, including the bilateral maxillary sinuses, was created to simulate NO distribution in the nasal cavity during normal breathing.
To describe a rare case of spindle cell tumor in the nasal cavity of a young female, along with its successful surgical management using a low-temperature plasma knife. A 38-year-old female patient presented with a 6-month history of nasal blockage, hyposmia, and local tenderness. The patient denied a history of definite diagnosis or special treatment.
View Article and Find Full Text PDFJ Cancer Res Clin Oncol
December 2022
Purpose: The purpose of this study was to investigate and analyze the level of actual participation and perceived importance of shared decision-making on treatment and care of lung cancer patients, to compare their differences and to explore their influencing factors.
Methods: A total of 290 lung cancer patients were collected from oncology and thoracic surgery departments of a comprehensive medical center in Qingdao from October 2018 to December 2019. Participants completed a cross-sectional questionnaire to assess their actual participation and perceived importance in shared decision-making on treatment and care.
Acta Otolaryngol
February 2022
Background: Suspension laryngoscopy (SL) is a common procedure performed by otolaryngologists. Studies have shown that adverse effects occur often during SL.
Objectives: To demonstrate the value of clinical application, this study compared the surgical time and postoperative oropharyngeal complications of SL using a novel curved video suspension laryngoscope with those of conventional SL.
This study evaluated the effects of dietary gallic acid (GA) on growth performance, diarrhea incidence and plasma antioxidant status of weaned piglets regardless of whether weaning weight was high or low. A total of 120 weaned piglets were randomly allocated to four treatments in a 42-day experiment with a 2 × 2 factorial treatment arrangement comparing different weaning weights (high weight (HW) or low weight (LW), 8.49 ± 0.
View Article and Find Full Text PDFLin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
October 2021
To measure the normal value of nasal nitric oxide(nNO) concentration of 50 healthy adults in Dalian. By investigating the changing trend of nitric oxide accumulation concentration in the nasal cavity when changing the duration of nasal non-ventilation under quiet state, to provide ideas for the noninvasive detection of the concentration of nitric oxide in the sinus and the patency of the sinus ostium. ①The left and right nNO concentrations(LnNO, RnNO) of 50 healthy subjects in Dalian were measured by Sunvou-CA2122(Wuxi), and the LnNO₁₀, LnNO₂₀, and LnNO₃₀ were measured through the left nasal cavity when the the time of nasal non ventilation was set for 10 s, 20 s, 30 s respectively.
View Article and Find Full Text PDFPurpose: The present study aimed to investigate the status and significantly influencing factors of treatment and prognosis perceptions among advanced cancer patients based on patient-reported outcome.
Methods: A cross-sectional study was conducted at two tertiary A general hospitals. From June to September 2019, 300 patients were invited and 292 of them participated in this study.
Background: Laryngeal cancer (LaC) remains one of the most common tumors of the respiratory tract with higher incidence in men than in women. The larynx is a small but vital organ on the neck. The dysfunction of the larynx can cause serious health problems such as hoarseness, respiratory distress, and dysphonia.
View Article and Find Full Text PDFFrom a biomechanical point of view, the process of Benign paroxysmal positional vertigo (BPPV) includes 2 fluid¯solid coupling effects: the interaction between particles and endolymph and the interaction between endolymph and cupula. The interaction between the canaliths and the wall would affect the coupling effects. This study aimed to investigate the entire process of cupula motion caused by canaliths motion and the influence of canalith particles composition.
View Article and Find Full Text PDFAim: This study aimed to investigate the relationships among hope, meaning in life, and post-traumatic growth (PTG) in patients with chronic obstructive pulmonary disease.
Design: A cross-sectional study design.
Methods: Between October 2018-September 2019, 221 chronic obstructive pulmonary disease patient completed the questionnaires including sociodemographic information, Chinese Version of Herth Hope Index, Meaning in Life Questionnaire, and Post-traumatic Growth Inventory.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
April 2020
Clinical manifestations were pharyngalgia, dysphagia and hoarseness. A laryngeal CT imaging demonstrated a destroyed consecutive lamina cartilaginis thyroidea. The clinical diagnose indicates that it is likely amalignant disease.
View Article and Find Full Text PDFNasopharyngeal carcinoma (NPC) is one of the most severe types of malignant cancer of the head and neck as it is difficult to treat. Ezrin is highly expressed in numerous types of cancer. However, the role of Ezrin in NPC has not been fully investigated and further studies are required in order to uncover its therapeutic potential in the treatment of NPC.
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