Publications by authors named "Jiyun Kwak"
Article Synopsis
- Dysregulated immune responses during infections can cause sepsis, leading to multiple organ dysfunction and highlighting the need for new treatment approaches.
- CE9A215 (inotodiol), a compound derived from fungi, has shown potential anti-inflammatory effects by reducing pro-inflammatory cytokines in both cell cultures and animal models.
- The study found that CE9A215 improved survival in mice with sepsis while promoting the clearance of harmful lipopolysaccharides by enhancing specific proteins associated with lipid transport, suggesting its potential as a new therapy for sepsis.
Biosynthesis of artificial starch and microbial protein from agricultural residue.
Sci Bull (Beijing)
January 2023
Growing populations and climate change pose great challenges to food security. Humankind is confronting a serious question: how will we feed the world in the near future? This study presents an out-of-the-box solution involving the highly efficient biosynthesis of artificial starch and microbial proteins from available and abundant agricultural residue as new feed and food sources. A one-pot biotransformation using an in vitro coenzyme-free synthetic enzymatic pathway and baker's yeast can simultaneously convert dilute sulfuric acid-pretreated corn stover to artificial starch and microbial protein under aerobic conditions.
View Article and Find Full Text PDFEscherichia coli mutant TBP38 lacks glycogen synthase (GlgA) and maltodextrin phosphorylase (MalP). When grown on maltose in fed-batch fermentation TBP38 accumulated more than 50-fold higher glycogen-type polysaccharide than its parental strain. The polysaccharides were extracted at different growth stages and migrated as one peak in size-exclusion chromatography.
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