Hypercholesterolemia represents a serious public health problem as it significantly increases the risk of developing cardiovascular diseases. Monacolin K (MK) in red yeast rice is an active compound that can effectively lower plasma cholesterol. To enhance the yield of MK in solid state fermentation of HNU01, the effects of different variables were systematically examined in single-factor experiments.
View Article and Find Full Text PDFBefore fermentation with hemicellulosic hydrolysate as a substrate, it is generally necessary to detoxify the toxic substances that are harmful to microorganism growth. Cyclic AMP receptor protein (CRP) is a global regulator, and mutation of its key sites may have an important impact on virulence tolerance. Using corncob hydrolysate without ion-exchange or lime detoxification as the substrate, shake flask fermentation experiments showed that CRP mutant IS5-dG (I112L, T127G, A144T) produced 18.
View Article and Find Full Text PDFSeventeen strains with wideranging decolorization ability were screened from contaminated soil and were applied on the decoloring of dye wastewater. Three strains were selected due to their high decolorization capacity on azo dyes, anthraquinone dyes and triphenylmethane dyes. The three strains were named as Strain I, Strain II, Strain III.
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