Oxygen reduction reaction kinetics of platinum-based catalysts under stress induction.

The ORR kinetic optimization for PtNi and PtPb catalysts is conferred by stress induction. First principles calculation shows the cleavage barrier reduction of the key intermediate *OOH to 28.48 and 0 kJ mol, respectively.

Erratum: PPAR δ inhibition protects against palmitic acid-LPS induced lipidosis and injury in cultured hepatocyte L02 cell: Erratum.

[This corrects the article DOI: 10.7150/ijms.37677.

Facile synthesis of L1-PtFe/C intermetallic catalysts with superior catalytic durability for the oxygen reduction reaction.

An o-PtFe/C intermetallic catalyst was prepared by a facile thermal reduction method with the average particle size of only 6.6 nm in the presence of urea. The loss of mass activity is only 25.

Enhanced Oxygen Reduction Reaction Performance by Adsorbed Water on Edge Sites.

Pt-based alloy nanoparticles have broad application prospects as cathode catalyst materials for proton-exchange membrane fuel cells (PEMFCs). Optimization of the oxygen adsorption energy is crucial to boost the performance of oxygen reduction catalysis. We successfully synthesized well-dispersed PtNi tetrahedra and obtained the PtNi/C catalyst adopting the one-pot synthetic protocol, which exhibits superb activity and good long-term stability for oxygen reduction reaction (ORR), achieving a mass activity of 1.

Could Be a Potential Marker for Diagnosis and Prognosis in Glioma.

(1) Background: Glioma is among the most common brain tumors, and is difficult to eradicate with current therapeutic strategies due to its highly invasive and aggressive characteristics. Sestrin2 () is an autophagy inducer. The effect of on glioma is controversial and unclear.

A meta-analysis of based radiomics for predicting lymph node metastasis in patients with biliary tract cancers.

Background: To assess the predictive value of radiomics for preoperative lymph node metastasis (LMN) in patients with biliary tract cancers (BTCs).

Methods: PubMed, Embase, Web of Science, Cochrane Library databases, and four Chinese databases [VIP, CNKI, Wanfang, and China Biomedical Literature Database (CBM)] were searched to identify relevant studies published up to February 10, 2022. Two authors independently screened all publications for eligibility.

Differences in Supragingival Microbiome in Patients with and without Full-Crown Prostheses.

To characterize the microflora profile of supragingival biofilm in patients with and without full-crown prostheses. Plaque samples of full-crown prostheses and teeth in patients with porcelain-fused-to-metal crowns, all-ceramic crowns, and no prostheses were collected (three patients per group), using 16S rRNA high-throughput sequencing technology to conduct DNA sequencing on the samples and using Qiime, R, and PICRUSt2 software to perform bioinformatics analyses and functional analyses on sequencing data. In total, 110,209 valid sequences were obtained in the experiment, corresponding to 11 phyla and 120 genera.

Obstructive sleep apnea and serum total testosterone: a system review and meta-analysis.

Purpose: Testosterone deficiency (TD) negatively affects male sexuality, reproduction, general health, and quality of life. In recent years, decreased serum testosterone levels have been reported to be caused by obstructive sleep apnea (OSA). However, these results are controversial and lack the support of a large number of high-quality studies.

[Effect of orthodontic traction on the microstructure of dental enamel].

Objective: To investigate the effect of orthodontic traction on the microstructure of dental enamel.

Methods: Forty-eight isolated premolars were randomly divided into 6 groups (=8), including Group A (blank control group), in which the teeth were bonded with the orthodontic brackets without any loading force; Groups B1, B2, and B3 where the teeth were bonded with the orthodontic brackets using clinical adhesives and loaded with 50 g force for 6 months, 200 g force for 6 months, and 200 g force for 1 month, respectively; and Groups C1 and C2, where the teeth were bonded with straight wire brackets using light curing bonding and chemical curing bonding techniques, respectively. All the teeth were embedded with non-decalcified epoxy resin.

PPAR δ inhibition protects against palmitic acid-LPS induced lipidosis and injury in cultured hepatocyte L02 cell.

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, and its pathogenesis and mechanism are intricate. In the present study, we aimed to evaluate the role of PPAR δ in LPS associated NAFLD and to investigate the signal transduction pathways underlying PPAR δ treatment in vitro. L02 cells were exposed to palmitic acid (PA) and/or LPS in the absence or presence of PPAR δ inhibition and/or activation.

[Involvement of heme oxygenase in PM2.5-toxicity in human umbilical vein endothelial cells].

Objective: To investigate the involvement of heme oxygenase (HO-1) in PM2.5 induced toxic responses in human umbilical vein endothelial cells (HUVECs).

Methods: The experiment groups are as follows: (1) control group; (2) PM2.

[Effect of ginsenoside on fine particulate matter induced oxidative injury in human endothelial cells].

Objective: To explore the mechanism of fine particulate matter (PM(2.5)) induced endothelial injury and the efficacy and mechanism of ginsenoside Rg1 on the inhibition of endothelium injuries in human endothelial cells exposure to PM(2.5).

[The comparison study on effects of water-soluble components of fine particulate matter on vasomotor functions in aortas from rats after exposure in different time].

Objective: To compare the difference of vasomotor functions in aortas segments from Wistar rats between 1-hour and 6-hours after exposure of water-soluble components of fine particulate matter (PM2.5).

Methods: All 30 Wistar rats were assigned to five groups (n=6 for each group) at random: the blank control group, control group for 1-hour and 6-hours, exposure group for 1-hour and 6-hours.

[Study of effects of drugs on myocardial hypertrophy due to overload].

Objective: To study the relation of expression change of tumor necrosis factor-alpha (TNF-alpha), angiotensin II (Ang II), and endothelin-1 (ET-1), and the effect of imidapril on myocardial hypertrophy due to overload.

Methods: Sixty-three rats were randomly divided into four groups: sham operation (n=15), overload group (n=16), imidapril group (n=16), and Caweidiluo group (n=16). Hypertrophic myocardium was reproduced in rats by constricting abdominal aorta.

Inotropic effects of MCI-154 on rat cardiac myocytes.

Calcium sensitizers exert positive inotropic effects without increasing intracellular Ca(2+). Thus, they avoid the undesired effects of Ca(2+) overload such as arrhythmias and cell injury, but most of them may impair myocyte relaxation. However, MCI-154, also a calcium sensitizer, has no impairment to cardiomyocyte relaxation.

Inhibition of Na+/Ca2+ exchange by hexapeptide FRCRSFa in rat ventricular myocytes.

Aim: To study the effect of Phe-Arg-Cys-Arg-Ser-Phe-CONH2 (FRCRSFa) on Na+/Ca2+ exchange and its specificity in rat ventricular myocytes.

Methods: Na+/Ca2+ exchange current (INa+/Ca2+) and other currents were measured using whole-cell voltage clamp technique.

Results: A concentration-dependent inhibition of hexapeptide FRCRSFa on Na +/Ca2+ exchange was observed in rat ventricular myocytes.