Effect of Nonsurgical Spinal Decompression on Intensity of Pain and Herniated Disc Volume in Subacute Lumbar Herniated Disc.

Objective: Nonsurgical spinal decompression therapy (NSDT) is a conservative treatment for the lumbosacral herniated intervertebral disc (L-HIVD). This study aimed to evaluate the clinical effectiveness of the NSDT and change in disc volume through magnetic resonance imaging (MRI) in subacute L-HIVD.

Methods: Sixty patients with subacute L-HIVD were randomized into either the decompression group (group D,  = 30) or the nondecompression group (group N,  = 30).

Effect of epidural polydeoxyribonucleotide in a rat model of lumbar foraminal stenosis.

Background: We aimed to investigate the effect of epidural polydeoxyribonucleotide (PDRN) on mechanical allodynia and motor dysfunction in a rat model of lumbar foraminal stenosis (LFS).

Methods: This study was conducted in two stages, using male Sprague-Dawley rats. The rats were randomly divided into eight groups.