Extended depth of focus contact lenses vs. two commercial multifocals: Part 2. Visual performance after 1 week of lens wear.

Purpose: To compare the visual performance of prototype contact lenses designed via deliberate manipulation of higher-order spherical aberrations to extend-depth-of-focus with two commercial multifocals, after 1 week of lens wear.

Methods: In a prospective, participant-masked, cross-over, randomized, 1-week dispensing clinical-trial, 43 presbyopes [age: 42-63 years] each wore AIROPTIX Aqua multifocal (AOMF), ACUVUE OASYS for presbyopia (AOP) and extended-depth-of-focus prototypes (EDOF) appropriate to their add requirements. Measurements comprised high-contrast-visual-acuity (HCVA) at 6m, 70cm, 50cm and 40cm; low-contrast-visual-acuity (LCVA) and contrast-sensitivity (CS) at 6m and stereopsis at 40cm.

Short-Term Adaptation of Accommodative Responses in Myopes Fitted With Multifocal Contact Lenses.

Objectives: To investigate whether adaptation of accommodative responses occurred in non-presbyopic myopes fitted with four multifocal contact lens (MFCL) designs.

Methods: Prospective, subject-masked clinical investigation comprising 40 experienced myopic lens wearers (18-25 years) fitted bilaterally with single-vision (SV) control lens (Air Optix Aqua [Alcon, Fort Worth, TX]) and randomized to two of four test MFCL (Proclear MFCL [Distance and Near] [CooperVision, Pleasanton, CA], Air Optix Aqua MFCL, Purevision MFCL [Bausch & Lomb, Rochester, NY]). Lenses were dispensed on a daily wear basis and worn for a minimum of 8 (maximum 14) days over three assessment visits, with a 1-week wash out between stages.

Short-term visual performance of soft multifocal contact lenses for presbyopia.

Purpose: To compare visual acuity (VA), contrast sensitivity, stereopsis, and subjective visual performance of Acuvue® Oasys® for Presbyopia (AOP), Air Optix® Aqua Multifocal (AOMF), and Air Optix® Aqua Single Vision (AOSV) lenses in patients with presbyopia.

Methods: A single-blinded crossover trial was conducted. Twenty patients with mild presbyopia (add ≤+1.

Short-term comparison between extended depth-of-focus prototype contact lenses and a commercially-available center-near multifocal.

Purpose: To compare the visual performance of prototype contact lenses which extend depth-of-focus (EDOF) by deliberate manipulation of multiple higher-order spherical aberration terms and a commercially-available center-near lens (AIR OPTIX Aqua Multifocal, AOMF).

Methods: This was a prospective, cross-over, randomized, single-masked (participant), short-term clinical trial where 52 participants (age 45-70 years) were stratified as low, medium or high presbyopes and wore EDOF and AOMF on different days. Objective measures comprised high and low contrast visual acuity (HCVA/LCVA, logMAR), and contrast sensitivity (log units) at 6m; HCVA at 70cm, 50cm and 40cm and stereopsis (seconds of arc) at 40cm.

Short-Term Visual Performance of Novel Extended Depth-of-Focus Contact Lenses.

Purpose: To compare the objective and subjective visual performance of a novel contact lens which extends depth of focus by deliberate manipulation of higher-order spherical aberrations and a commercially available zonal-refractive multifocal lens.

Methods: A prospective, cross-over, randomized, single-masked, short-term clinical trial comprising 41 presbyopes (age 45 to 70 years) wearing novel Extended Depth of Focus lenses (EDOF) and ACUVUE OAYS for Presbyopia (AOP). Each design was assessed on different days with a minimum overnight wash-out.

Visual performance of single vision and multifocal contact lenses in non-presbyopic myopic eyes.

Purpose: To assess visual performance of single vision and multifocal soft contact lenses.

Methods: At baseline, forty-four myopic participants (aged 18-35 years) were fitted bilaterally with a control lens (AirOptix Aqua). At the four follow-up visits, a total of 16 study lenses (5 single vision, 11 multifocal lenses) were fitted contralaterally.