Protective Effect of Deer Heart Peptide on Cardiac Injury in Mice.

Peptides are widely used as natural bio-small molecules because of their various pharmacological activities such as enhancing immunity, promoting wound healing, and improving inflammation. Alcoholic heart injury has become one of the major health problems worldwide, and alcohol consumption is now the main cause of alcoholic cardiomyopathy. In this study, deer heart peptides were extracted from deer hearts by enzymatic digestion and the antioxidant activity of deer heart peptides extracted at different times was evaluated by three in vitro antioxidant methods, and the active peptide with the best enzymatic effect has been selected for in vivo animal experiments.

Jinmaitong alleviates diabetic neuropathic pain by inhibiting JAK2/STAT3 signaling in microglia of diabetic rats.

Ethnopharmacological Relevance: Jinmaitong (JMT) is a prescription of Traditional Chinese Medicine that is composed of 12 crude drugs. It has been used in the treatment of diabetic neuropathic pain (DNP) for more than 30 years.

Aim Of Study: Microglia are thought to play an important role in neuropathic pain.

Characteristics and Influence Factors of Pb(II) Adsorption by Graphene Oxide-Montmorillonite Composite.

This study presents the fabrication of a novel porous composite of graphene oxide-montmorillonite (GO-MMT) through the modification of montmorillonite using the freeze-drying method for the purpose of Pb removal. The characterization of the GO-MMT composite was conducted using scanning electron microscopy, Fourier transform infrared spectrometry, and X-ray diffraction. The results from batch adsorption experiments revealed that the GO-MMT composite exhibited a superior capacity for Pb removal compared to MMT.

Significant Enhanced SO Resistance of Pt/SiO Catalysts by Building the Ultrathin Metal Oxide Shell for Benzene Catalytic Combustion.

A noble metal catalyst shows excellent low-temperature oxidation activity in the catalytic combustion of benzene but has the problem of SO poisoning. We all know that SO easily competes with the reactant molecules for adsorption of the active site and has electronic effects on the active site to deactivate the catalyst. Therefore, the sulfur resistance of catalysts is the key problem to be solved in the process of catalytic combustion of benzene.

Core-shell CoCuO@MO (MNb, Ti and Ce) catalysts with outstanding durability and resistance to HO for the catalytic combustion of o-dichlorobenzene.

Configuring Co-based catalysts with excellent activity, durability, anti-HO capability and superior chlorine resistance is an effective strategy for catalytic combustion of CVOCs. In this work, we elaborated a CoCuO catalysts with the same core but different shell. The CoCuO dodecahedron surface was successfully coated with shells of NbO, TiO, and CeO using a range of conventional synthesis methods.

Relationship between DHX15 expression and survival in colorectal cancer.

Objective: to explore the relationship between the expression of DEAH-box RNA helicase 15 (DHX15) in colorectal cancer (CRC), its clinical pathological features and survival.

Method: DHX15 expression data with clinical pathological features from the Cancer Gene Atlas (TCGA) and the Clinical Proteomic Tumor Analysis Consortium (CPTAC) were statistically analyzed for the association between DHX15 expression and overall survival in CRC. The expression of DHX15 was performed by immunohistochemical staining (IHC) using tumor and the adjacent normal tissue, mounted in tissue microarrays.

Engineering yolk-shell MnFe@CeO@TiO nanocages as a highly efficient catalyst for selective catalytic reduction of NO with NH at low temperatures.

To broaden the reaction temperature range and improve the HO-resistance of manganese-based catalysts, yolk-shell structured MnFe@CeO@TiO nanocages were prepared. The CeO shell could effectively increase the oxygen vacancy defect sites, and the TiO shell could remarkably improve the surface acid sites. Combining the advantages of the two shells could effectively solve the above questions.

Extracting Wetland Type Information with a Deep Convolutional Neural Network.

Wetlands have important ecological value. The application of wetland remote sensing is essential for the timely and accurate analysis of the current situation in wetlands and dynamic changes in wetland resources, but high-resolution remote sensing images display nonobvious boundaries between wetland types. However, high classification accuracy and time efficiency cannot be guaranteed simultaneously.

Construction of Superhydrophobic Ru/TiCeO Catalysts for the Enhanced Water Resistance of -Dichlorobenzene Catalytic Combustion.

In this paper, a simple method to enhance the HO resistance of Ru/TiCeO catalysts for -DCB catalytic combustion by constructing superhydrophobic coating of phenyltriethoxysilane (PhTES) was proposed. The effect of PhTES content on the pore structure, specific surface area, HO resistance, contact angle (CA) value, and catalytic activity of the catalyst was studied. When water was added, the pristine Ru/TiCeO catalytic activity decreased by about 26%, while the Ru/TiCeO-16Ph activity hardly decreased.

Silencing () in Switchgrass ( L.) Improves Lignocellulosic Biofuel Production.

Switchgrass ( L.) is a lignocellulosic perennial grass with great potential in bioenergy field. Lignocellulosic bioenergy crops are mostly resistant to cell wall deconstruction, and therefore yield suboptimal levels of biofuel.

Precise design and synthesis of Pd/InO@CoO core-shell nanofibers for the highly efficient catalytic combustion of toluene.

In this work, Pd/InO@CoO core-shell nanofibers, CoO@Pd/InO core-shell nanofibers and Pd/InO/CoO nanofibers with different morphologies have been successfully synthesized for the catalytic combustion of toluene. Among them, the Pd/InO@CoO core-shell sample is novel and composed of Pd/InO nanotube cores, CoO nanocubes and CoO nanoparticle shells derived from ZIF-67. On the contrary, the CoO@Pd/InO core-shell catalyst is assembled by CoO nanocube cores and Pd/InO nanotube shells.

Expression and protease characterization of a conserved protein YgjD in .

The glycopeptidase GCP and its homologue proteins are conserved and essential for survival of bacteria. The gene (Glycopeptidase homologue) was cloned from strain SF-1. The gene consisted of 1,017 bp, which encodes a 338 amino acid polypeptide.

Functional Analysis of Cellulose Synthase and Genes in Switchgrass () by Overexpression and RNAi-Mediated Gene Silencing.

Switchgrass ( L.) is a leading lignocellulosic bioenergy feedstock. Cellulose is a major component of the plant cell walls and the primary substrate for saccharification.

Sugar release and growth of biofuel crops are improved by downregulation of pectin biosynthesis.

Cell walls in crops and trees have been engineered for production of biofuels and commodity chemicals, but engineered varieties often fail multi-year field trials and are not commercialized. We engineered reduced expression of a pectin biosynthesis gene (Galacturonosyltransferase 4, GAUT4) in switchgrass and poplar, and find that this improves biomass yields and sugar release from biomass processing. Both traits were maintained in a 3-year field trial of GAUT4-knockdown switchgrass, with up to sevenfold increased saccharification and ethanol production and sixfold increased biomass yield compared with control plants.

Development and use of a switchgrass ( L.) transformation pipeline by the BioEnergy Science Center to evaluate plants for reduced cell wall recalcitrance.

Background: The mission of the BioEnergy Science Center (BESC) was to enable efficient lignocellulosic-based biofuel production. One BESC goal was to decrease poplar and switchgrass biomass recalcitrance to biofuel conversion while not affecting plant growth. A transformation pipeline (TP), to express transgenes or transgene fragments (constructs) in these feedstocks with the goal of understanding and decreasing recalcitrance, was considered essential for this goal.

Downregulation of a UDP-Arabinomutase Gene in Switchgrass ( L.) Results in Increased Cell Wall Lignin While Reducing Arabinose-Glycans.

Switchgrass ( L.) is a C perennial prairie grass and a dedicated feedstock for lignocellulosic biofuels. Saccharification and biofuel yields are inhibited by the plant cell wall's natural recalcitrance against enzymatic degradation.

Identification and Overexpression of a Knotted1-Like Transcription Factor in Switchgrass (Panicum virgatum L.) for Lignocellulosic Feedstock Improvement.

High biomass production and wide adaptation has made switchgrass (Panicum virgatum L.) an important candidate lignocellulosic bioenergy crop. One major limitation of this and other lignocellulosic feedstocks is the recalcitrance of complex carbohydrates to hydrolysis for conversion to biofuels.

Global gene expression profiling of two switchgrass cultivars following inoculation with Burkholderia phytofirmans strain PsJN.

Improvement and year-to-year stabilization of biomass yields are primary objectives for the development of a low-input switchgrass feedstock production system using microbial endophytes. An earlier investigation of the effect of Burkholderia phytofirmans strain PsJN on switchgrass germplasm demonstrated differential responses between genotypes. PsJN inoculation of cv.

Identification and overexpression of gibberellin 2-oxidase (GA2ox) in switchgrass (Panicum virgatum L.) for improved plant architecture and reduced biomass recalcitrance.

Gibberellin 2-oxidases (GA2oxs) are a group of 2-oxoglutarate-dependent dioxygenases that catalyse the deactivation of bioactive GA or its precursors through 2β-hydroxylation reaction. In this study, putatively novel switchgrass C20 GA2ox genes were identified with the aim of genetically engineering switchgrass for improved architecture and reduced biomass recalcitrance for biofuel. Three C20 GA2ox genes showed differential regulation patterns among tissues including roots, seedlings and reproductive parts.

Global reprogramming of transcription and metabolism in Medicago truncatula during progressive drought and after rewatering.

Medicago truncatula is a model legume forage crop native to the arid and semi-arid environments of the Mediterranean. Given its drought-adapted nature, it is an ideal candidate to study the molecular and biochemical mechanisms conferring drought resistance in plants. Medicago plants were subjected to a progressive drought stress over 14 d of water withholding followed by rewatering under controlled environmental conditions.

Overexpression of AtLOV1 in Switchgrass alters plant architecture, lignin content, and flowering time.

Background: Switchgrass (Panicum virgatum L.) is a prime candidate crop for biofuel feedstock production in the United States. As it is a self-incompatible polyploid perennial species, breeding elite and stable switchgrass cultivars with traditional breeding methods is very challenging.

Development of an integrated transcript sequence database and a gene expression atlas for gene discovery and analysis in switchgrass (Panicum virgatum L.).

Switchgrass (Panicum virgatum L.) is a perennial C4 grass with the potential to become a major bioenergy crop. To help realize this potential, a set of RNA-based resources were developed.

Overexpression of miR156 in switchgrass (Panicum virgatum L.) results in various morphological alterations and leads to improved biomass production.

Switchgrass (Panicum virgatum L.) has been developed into a dedicated herbaceous bioenergy crop. Biomass yield is a major target trait for genetic improvement of switchgrass.

Analysis of tall fescue ESTs representing different abiotic stresses, tissue types and developmental stages.

Background: Tall fescue (Festuca arundinacea Schreb) is a major cool season forage and turf grass species grown in the temperate regions of the world. In this paper we report the generation of a tall fescue expressed sequence tag (EST) database developed from nine cDNA libraries representing tissues from different plant organs, developmental stages, and abiotic stress factors. The results of inter-library and library-specific in silico expression analyses of these ESTs are also reported.